Ma B, Wang Y, Zhang H, Zhang X
Clin Exp Obstet Gynecol. 2014;41(1):37-40.
Laser-assisted hatching (LAH) is recognized as a useful technology to improve clinical pregnancy rates and implantation rates. This study reports the differences between a new LAH method and two conventional LAH techniques.
The authors studied 151 patients with repeated implantation failure, who were divided into three groups.
In group 1, the zona pellucida (ZP) was opened using LAH (n = 52). In group 2, laser-assisted thinning was performed to dissolve the outer layer of the ZP (n = 49). In group 3, laser-assisted thinning was performed to dissolve the inner layer of the ZP (n = 50). The clinical pregnancy rates and implantation rates among the groups were compared. The results demonstrate that there are significant differences in the clinical pregnancy rates and implantation rates between group 3 and the other two groups.
Performing laser-assisted thinning to dissolve the inner layer of the ZP markedly increases the pregnancy rates and implantation rates of patients with repeated implantation failure.
激光辅助孵化（LAH）被认为是一种提高临床妊娠率和着床率的有用技术。本研究报告了一种新的LAH方法与两种传统LAH技术之间的差异。
作者研究了151例反复着床失败的患者，将其分为三组。
第1组采用LAH打开透明带（ZP）（n = 52）。第2组进行激光辅助减薄以溶解ZP的外层（n = 49）。第3组进行激光辅助减薄以溶解ZP的内层（n = 50）。比较了各组之间的临床妊娠率和着床率。结果表明，第3组与其他两组之间的临床妊娠率和着床率存在显著差异。
进行激光辅助减薄以溶解ZP的内层可显著提高反复着床失败患者的妊娠率和着床率。
