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头颈部肿瘤动脉内细胞毒性治疗后的长期研究

[Long-term studies after intra-arterial cytostatic therapy of head and neck tumors].

作者信息

Szabó G, Kovács A, Gyenes V, Suba Z

出版信息

Orv Hetil. 1989 Apr 16;130(16):823-6.

PMID:2471128
Abstract

This study on selected tumour patients demonstrates relationship between the effectiveness of preoperative, postoperative and palliative intra-arterial cytostatic treatment of tumours of the head and neck and the long-term survival. During the period ranging between 3.5 and 9 years after preoperative treatment of 11 cases, palliative treatment of 6 cases, resulting in 100% tumour regression, and postoperative-adjuvant treatment of 23 cases (selected from 254 cases receiving intra-arterial treatment), local recurrence was observed in 10 cases. The question is raised of the necessity of radical surgery corresponding to the original tumour after preoperative treatment resulting in a completely tumour-free state.

摘要

这项针对特定肿瘤患者的研究表明,头颈部肿瘤术前、术后及姑息性动脉内细胞毒性治疗的有效性与长期生存率之间存在关联。在对11例患者进行术前治疗、6例患者进行姑息治疗(肿瘤消退率达100%)以及23例患者(从254例接受动脉内治疗的患者中选取)进行术后辅助治疗后的3.5至9年期间,观察到10例局部复发。对于术前治疗后达到完全无瘤状态的患者,是否有必要针对原发肿瘤进行根治性手术这一问题由此提出。

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