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18F-FDG PET/CT在肉瘤治疗中的临床应用

[Clinical application of 18F-FDG PET/CT in the treatment of sarcomas].

作者信息

Borbély Katalin, Németh Zsuzsanna, Kásler Miklós

机构信息

PET/CT Ambulancia, Országos Onkológiai Intézet, Budapest, Hungary.

Onkológiai Osztály, Szent Margit Kórház, Budapest, Hungary.

出版信息

Magy Onkol. 2014 Mar;58(1):24-31. Epub 2014 Feb 20.

Abstract

[18F]-Fluoro-deoxyglucose positron emission tomography / computer tomography (18F-FDG PET/CT) is able to detect and assess the abnormal metabolism, enabling visualization and quantification in vivo with integration into CT anatomic information. The clinical usefulness of FDG PET/CT in the management of patients with sarcomas has been assessed by numerous investigators. Sarcomas are solid malignant tumors with distinct clinical and pathological features. Effective management of patients with sarcoma requires accurate diagnosis and staging. The authors discuss the major indications of PET/CT on the basis of literature data for diagnosis, staging, guidance of biopsy and monitoring response to therapy in both primary bone and soft tissue tumors. The consistent use of PET molecular imaging methods is of high importance in characterizing and understanding sarcoma behavior in clinical practice.

摘要

[18F] - 氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(18F - FDG PET/CT)能够检测和评估异常代谢,通过整合CT解剖信息实现体内可视化和定量分析。众多研究者评估了FDG PET/CT在肉瘤患者管理中的临床应用价值。肉瘤是具有独特临床和病理特征的实体恶性肿瘤。对肉瘤患者进行有效管理需要准确的诊断和分期。作者基于文献数据讨论了PET/CT在原发性骨肿瘤和软组织肿瘤的诊断、分期、活检引导及治疗反应监测方面的主要适应证。在临床实践中,持续应用PET分子成像方法对于表征和理解肉瘤行为至关重要。

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