Gautam A K, Gandhi D N, Jani J P, Venkatakrishna-Bhatt H, Chowdhury A R
National Institute of Occupational Health, Ahmedabad, India.
Res Commun Chem Pathol Pharmacol. 1989 Mar;63(3):463-6.
The effect of hexachlorocyclohexane (HCH) treatment in male albino rats at dosages of 3 and 6 mg/kg body weight by force-feeding were studied over a period of 180 days. Histological observations revealed graded degeneration in the muscular layer of vas deferens. Moreover, the accumulation of HCH residue in serum and vas deferens is highly significant in the experimental group. The contractility of muscles showed marked inhibition by in vitro study.
通过强制喂食，研究了六氯环己烷（HCH）以3和6毫克/千克体重的剂量对雄性白化大鼠的影响，为期180天。组织学观察显示输精管肌层出现分级变性。此外，实验组血清和输精管中六氯环己烷残留的积累非常显著。体外研究表明肌肉收缩性受到明显抑制。
