Barkas Fotis, Liberopoulos Evangelos, Kei Anastazia, Elisaf Moses
Department of Internal Medicine, University of Ioannina Medical School, Ioannina, Greece.
Ann Gastroenterol. 2013;26(1):23-28.
INFLAMMATORY BOWEL DISEASE (IBD) IS A CHRONIC INFLAMMATORY INTESTINAL DISORDER ENCOMPASSING TWO MAJOR ENTITIES: Crohn's disease and ulcerative colitis. Intestinal inflammatory processes reduce the absorption of sodium, chloride and calcium, while they increase potassium secretion. In addition, mild to severe metabolic alkalosis may occur in IBD patients, mainly depending on the severity of the disease and the part of the gastrointestinal tract being affected. The aim of this review is the presentation of the electrolyte and acid-base disturbances in IBD and how the activity state of the disease and/or treatment may affect them.
炎症性肠病（IBD）是一种慢性肠道炎症性疾病，包括两种主要类型：克罗恩病和溃疡性结肠炎。肠道炎症过程会减少钠、氯和钙的吸收，同时增加钾的分泌。此外，IBD患者可能会出现轻度至重度的代谢性碱中毒，这主要取决于疾病的严重程度和受影响的胃肠道部位。本综述的目的是介绍IBD中的电解质和酸碱紊乱，以及疾病的活动状态和/或治疗如何影响它们。
