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体育训练作为神经心源性晕厥的非药物治疗方法。

Physical training as non-pharmacological treatment of neurocardiogenic syncope.

出版信息

Arq Bras Cardiol. 2014 Mar;102(3):288-94. doi: 10.5935/abc.20140021.

DOI:10.5935/abc.20140021
PMID:24714795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3987313/
Abstract

BACKGROUND

Characterized as a sudden and temporary loss of consciousness and postural tone, with quick and spontaneous recovery, syncope is caused by an acute reduction of systemic arterial pressure and, therefore, of cerebral blood flow. Unsatisfactory results with the use of drugs allowed the nonpharmacological treatment of neurocardiogenic syncope was contemplated as the first therapeutic option.

OBJECTIVES

To compare, in patients with neurocardiogenic syncope, the impact of a moderate intensity aerobic physical training (AFT) and a control intervention on the positivity of head-up tilting test (HUT) and orthostatic tolerance time.

METHODS

Were studied 21 patients with a history of recurrent neurocardiogenic syncope and HUT. The patients were randomized into: trained group (TG), n = 11, and control group (CG), n = 10. The TG was submitted to 12 weeks of AFT supervised, in cycle ergometer, and the CG to a control procedure that consisted in 15 minutes of stretching and 15 minutes of light walk.

RESULTS

The TG had a positive effect to physical training, with a significant increase in peak oxygen consumption. The CG did not show any statistically significant change before and after the intervention. After the intervention period, 72.7% of the TG sample had negative results to the HUT, not having syncope in the revaluation.

CONCLUSION

The program of supervised aerobic physical training for 12 weeks was able to reduce the number of positive HUT, as it was able to increase tolerance time in orthostatic position during the HUT after the intervention period.

摘要

背景

晕厥是一种突然发生的、短暂的意识丧失和姿势性张力丧失,并伴有快速自发的恢复,其原因是全身动脉血压的急性降低,从而导致脑血流量减少。药物治疗效果不理想,促使人们考虑将神经心源性晕厥的非药物治疗作为首选治疗方案。

目的

比较神经心源性晕厥患者接受中等强度有氧运动训练(AFT)和对照干预对直立倾斜试验(HUT)阳性率和直立耐受时间的影响。

方法

研究了 21 例有反复发作神经心源性晕厥和 HUT 病史的患者。患者随机分为训练组(TG),n = 11 和对照组(CG),n = 10。TG 接受了 12 周的监督循环运动自行车 AFT,而 CG 则接受了 15 分钟伸展和 15 分钟轻走的对照程序。

结果

TG 对体能训练有积极影响,峰值摄氧量显著增加。CG 在干预前后均未显示出任何统计学上的显著变化。干预后,TG 样本中有 72.7%的 HUT 结果为阴性,在重新评估中没有发生晕厥。

结论

为期 12 周的监督有氧运动训练方案能够减少 HUT 的阳性率,因为它能够增加 HUT 期间直立位的耐受时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea5e/3987313/522a1d04f05f/abc-102-03-0288-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea5e/3987313/522a1d04f05f/abc-102-03-0288-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea5e/3987313/522a1d04f05f/abc-102-03-0288-g01.jpg

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本文引用的文献

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Clin Auton Res. 2008 Aug;18(4):179-86. doi: 10.1007/s10286-008-0481-0. Epub 2008 Aug 5.
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The effects of exercise training on arterial baroreflex sensitivity in neurally mediated syncope patients.运动训练对神经介导性晕厥患者动脉压力反射敏感性的影响。
Eur Heart J. 2007 Nov;28(22):2749-55. doi: 10.1093/eurheartj/ehm208. Epub 2007 Jun 7.
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The Second Prevention of Syncope Trial (POST II)--a randomized clinical trial of fludrocortisone for the prevention of neurally mediated syncope: rationale and study design.
运动员中非心源性晕厥的病理生理学。
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Cardiac Rehabilitation: Far Beyond Coronary Artery Disease.心脏康复:远不止于冠状动脉疾病。
Arq Bras Cardiol. 2015 Dec;105(6):549-51. doi: 10.5935/abc.20160002.
晕厥二级预防试验(POST II)——一项关于氟氢可的松预防神经介导性晕厥的随机临床试验:原理与研究设计
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[Clinical outcome of patients with neurocardiogenic syncope (NCS) after therapy interruption].
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Prevention of Syncope Trial (POST): a randomized, placebo-controlled study of metoprolol in the prevention of vasovagal syncope.晕厥预防试验(POST):一项关于美托洛尔预防血管迷走性晕厥的随机、安慰剂对照研究。
Circulation. 2006 Mar 7;113(9):1164-70. doi: 10.1161/CIRCULATIONAHA.105.535161. Epub 2006 Feb 27.
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Home orthostatic self-training in neurocardiogenic syncope.
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