Intralaboratory quality assurance of immunohistochemical procedures. Recommended practices for daily application.

During the past several decades, immunohistologic techniques have been developed that may provide important adjunctive information to the diagnostic pathologist. These procedures are now widely available and commonly used in the pathology laboratory. Proper performance of immunohistochemical procedures and interpretation of their results require development and implementation of appropriate quality control and quality assurance measures. This article reviews the application of quality control standards in the immunohistochemistry laboratory and the integration of these activities into the overall quality assurance program of the department.