Palkovits M, Kakucska I, Makara G B
First Department of Anatomy, Semmelweis University Medical School, Budapest, Hungary.
Brain Res. 1989 May 8;486(2):364-8. doi: 10.1016/0006-8993(89)90524-6.
Substance P-containing nerve fibers in the median eminence of rat arise in cells located in the arcuate nucleus. Two days following surgical lesioning of the median eminence immunoreactive substance P accumulated in neuronal perikarya in the middle part (rostrocaudally) of the arcuate nucleus, mainly in its ventromedial portion. Substance P-immunostained cells appeared nowhere else in the hypothalamus following surgical lesion of the median eminence while they were found in several hypothalamic and extrahypothalamic cell groups after colchicine treatment.
大鼠正中隆起中含P物质的神经纤维起源于弓状核中的细胞。正中隆起手术损伤两天后，免疫反应性P物质积聚在弓状核中部（前后方向）的神经元胞体中，主要在其腹内侧部分。正中隆起手术损伤后，下丘脑其他部位未出现P物质免疫染色细胞，而秋水仙碱处理后，在几个下丘脑和下丘脑外细胞群中发现了这些细胞。
