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部分肾切除术后肝素诱导的血小板减少症导致双侧肾上腺出血——病例报告

Bilateral adrenal hemorrhage due to heparin-induced thrombocytopenia following partial nephrectomy - a case report.

作者信息

Winter Ashley G, Ramasamy Ranjith

机构信息

Department of Urology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, 10065, USA.

Department of Urology, Baylor College of Medicine, Houston, Texas, 77030, USA.

出版信息

F1000Res. 2014 Jan 23;3:24. doi: 10.12688/f1000research.3-24.v1. eCollection 2014.

DOI:10.12688/f1000research.3-24.v1
PMID:24715975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3954162/
Abstract

Heparin-induced thrombocytopenia (HIT) can cause severe life-threatening events such as bilateral adrenal hemorrhage (BAH). A 48-year-old female developed a pulmonary embolus (PE) following partial nephrectomy. The anticoagulation treatment for her PE was complicated by HIT and subsequent BAH. To the author's knowledge, this is the first reported case of HIT-associated BAH following renal surgery.

摘要

肝素诱导的血小板减少症（HIT）可导致严重的危及生命的事件，如双侧肾上腺出血（BAH）。一名48岁女性在部分肾切除术后发生肺栓塞（PE）。她因PE接受的抗凝治疗因HIT及随后的BAH而变得复杂。据作者所知，这是首例肾手术后发生的与HIT相关的BAH病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c442/3954162/eae2d229e183/f1000research-3-3515-g0000.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c442/3954162/eae2d229e183/f1000research-3-3515-g0000.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c442/3954162/eae2d229e183/f1000research-3-3515-g0000.jpg

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本文引用的文献

1
Adrenal haemorrhage due to heparin-induced thrombocytopenia.肝素诱导的血小板减少症致肾上腺出血。
Thromb Haemost. 2013 Apr;109(4):669-75. doi: 10.1160/TH12-11-0865. Epub 2013 Feb 7.
2
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J Arthroplasty. 2012 Aug;27(7):1413.e15-8. doi: 10.1016/j.arth.2012.01.012. Epub 2012 Mar 6.
3
Chance favors the prepared mind: the association between heparin-induced thrombocytopenia and bilateral adrenal hemorrhage.
双侧肾上腺出血：肝素诱导的血小板减少症中血流动力学崩溃的一个原因。
BMJ Case Rep. 2016 Mar 10;2016:bcr2016214679. doi: 10.1136/bcr-2016-214679.
4
Bilateral adrenal haemorrhage associated with heparin-induced thrombocytopaenia during treatment of Fournier gangrene.在富尼埃坏疽治疗期间，双侧肾上腺出血与肝素诱导的血小板减少症相关。
BMJ Case Rep. 2014 Oct 14;2014:bcr2014206070. doi: 10.1136/bcr-2014-206070.
Crit Care Med. 2011 Apr;39(4):912-3. doi: 10.1097/CCM.0b013e31820e6be4.
4
Bilateral adrenal hemorrhage: the unrecognized cause of hemodynamic collapse associated with heparin-induced thrombocytopenia.双侧肾上腺出血：肝素诱导的血小板减少症相关血流动力学崩溃的未被识别原因。
Crit Care Med. 2011 Apr;39(4):833-8. doi: 10.1097/CCM.0b013e318206d0eb.