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通过电感耦合等离子体质谱法测定母体血液和羊水的元素。

Elements in maternal blood and amniotic fluid determined by ICP-MS.

作者信息

Silberstein Tali, Saphier Magal, Mashiach Yardena, Paz-Tal Ofra, Saphier Oshra

机构信息

Department of Gynecology and Obstetrics, Soroka University Hospital , Beer-Sheva , Israel .

出版信息

J Matern Fetal Neonatal Med. 2015 Jan;28(1):88-92. doi: 10.3109/14767058.2014.905907. Epub 2014 Apr 9.

DOI:10.3109/14767058.2014.905907
PMID:24716749
Abstract

OBJECTIVE

Knowledge about levels of toxic and non-toxic elements in amniotic fluid is limited. The aims of this study were: (1) to measure levels of trace elements Cu, Fe, Zn, B, Sr and Co in amniotic fluid and maternal serum during second trimester of pregnancy; and (2) to determine what correlations exists between elements levels in amniotic fluid and maternal serum.

METHODS

The levels of, iron, copper, zinc, cobalt, strontium and boron were measured in blood and amniotic fluid during genetic amniocentesis using inductively coupled plasma mass spectrometry (ICP-MS).

RESULTS

Concentrations of the elements: Fe, Cu, Zn, Co, Sr and B in amniotic fluid were significantly lower than in maternal blood. For iron, zinc, cobalt, strontium and boron there was a linear correlation between levels in amniotic fluid and maternal serum.

CONCLUSIONS

The concentration of trace elements in amniotic fluid was found to be lower than maternal serum and linearly correlated to its level.

摘要

目的

关于羊水中有毒和无毒元素水平的知识有限。本研究的目的是:(1)测量妊娠中期羊水和母血清中微量元素铜、铁、锌、硼、锶和钴的水平;(2)确定羊水和母血清中元素水平之间存在何种相关性。

方法

在遗传羊膜穿刺术期间,使用电感耦合等离子体质谱法(ICP-MS)测量血液和羊水中铁、铜、锌、钴、锶和硼的水平。

结果

羊水中铁、铜、锌、钴、锶和硼元素的浓度显著低于母血中的浓度。对于铁、锌、钴、锶和硼,羊水和母血清中的水平存在线性相关性。

结论

发现羊水中微量元素的浓度低于母血清,且与其水平呈线性相关。

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