Kavanaugh Brian, Holler Karen
a Department of Clinical Psychology , Antioch University New England , Keene , New Hampshire.
Appl Neuropsychol Child. 2014;3(2):126-34. doi: 10.1080/21622965.2012.731662. Epub 2012 Nov 20.
Although the relationship between executive dysfunction and depressive disorders has been well established in the adult population, research within the adolescent population has produced mixed results. The present study examined executive-functioning subdomains in varying levels of self-reported depression within an adolescent inpatient sample diagnosed with primary mood disorders. Via retrospective chart review, the sample consisted of those adolescents (ages 13-18 years) who completed a combined psychological/neuropsychological assessment during hospitalization (N = 105). When the sample was divided into adolescents with mood disorders with self-reported depressive symptoms and adolescents with mood disorders without self-reported depressive symptoms, no differences in various executive functions were identified. There were also no correlations between overall self-reported depressive symptoms and overall executive functioning. However, there were negative correlations between select executive subdomains (e.g., problem solving and response inhibition) and certain depressive symptom subdomains (e.g., negative mood and interpersonal problems). Based on these findings, there was no difference in executive functions between mood disorders with depressive symptoms and mood disorders without depressive symptoms, although there may be select executive subdomains that are particularly involved in certain depressive symptoms, providing important information for the treatment of adolescent depression.
虽然执行功能障碍与抑郁症之间的关系在成年人群体中已得到充分证实，但在青少年群体中的研究结果却参差不齐。本研究在一个被诊断为原发性情绪障碍的青少年住院样本中，考察了不同自我报告抑郁水平下的执行功能子领域。通过回顾性病历审查，样本包括那些在住院期间完成了综合心理/神经心理评估的青少年（年龄在13 - 18岁之间，N = 105）。当样本被分为有自我报告抑郁症状的情绪障碍青少年和无自我报告抑郁症状的情绪障碍青少年时，未发现各种执行功能存在差异。总体自我报告的抑郁症状与总体执行功能之间也没有相关性。然而，特定的执行功能子领域（如问题解决和反应抑制）与某些抑郁症状子领域（如消极情绪和人际问题）之间存在负相关。基于这些发现，有抑郁症状的情绪障碍和无抑郁症状的情绪障碍在执行功能上没有差异，尽管可能有特定的执行功能子领域特别涉及某些抑郁症状，这为青少年抑郁症的治疗提供了重要信息。
