Tunio Mutahir Ali, Al-Asiri Mushabbab, Fareed Muhammad Mohsin
Department of Radiation Oncology, Comprehensive Cancer Centre, King Fahad Medical City, Riyadh-59046, Saudi Arabia.
J Coll Physicians Surg Pak. 2014 Mar;24 Suppl 1:S20-1.
Uterine leiomyosarcoma is an uncommon and aggressive gynecologic malignancy with an overall poor prognosis. Lungs, bones and brain are common sites of metastases of uterine leiomyosarcoma. Metastases of uterine leiomyosarcoma to the heart are extremely rare, and only a few case reports have been published so far. Herein we present the case of 57 years old female, who had undergone total abdominal hysterectomy with salpingo-oophorectomy 10 years back for uterine leiomyosarcoma, she presented with dyspnea, dizziness, fever, and tachycardia, subsequently was found to have interventricular septum cardiac as well extensive system metastasis and recurrent pelvic mass. Patient's symptoms responded to palliative radiotherapy followed by chemotherapy.
子宫平滑肌肉瘤是一种罕见且侵袭性强的妇科恶性肿瘤,总体预后较差。肺、骨和脑是子宫平滑肌肉瘤常见的转移部位。子宫平滑肌肉瘤转移至心脏极为罕见,迄今为止仅有少数病例报告发表。在此,我们报告一例57岁女性病例,该患者10年前因子宫平滑肌肉瘤接受了全腹子宫切除术及双侧输卵管卵巢切除术,现出现呼吸困难、头晕、发热和心动过速,随后被发现有室间隔心肌转移以及广泛的全身转移和盆腔肿块复发。患者症状经姑息性放疗后再进行化疗得到缓解。