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[胸骨骨髓炎。病因、诊断及手术治疗理念]

[Sternal osteomyelitis. Etiology, diagnostics and operative therapy concepts].

作者信息

Hauser J, Steinau H U, Ring A, Lehnhardt M, Tilkorn D J

机构信息

Klinik für Plastische, Rekonstruktive und Ästhetische Chirurgie, Handchirurgie, Alfried Krupp Krankenhaus Essen-Steele, Hellweg 100, 45276, Essen, Deutschland,

出版信息

Chirurg. 2014 Apr;85(4):357-65; quiz 366-7. doi: 10.1007/s00104-013-2678-6.

DOI:10.1007/s00104-013-2678-6
PMID:24718446
Abstract

Deep sternal infections with sternal osteomyelitis are rare conditions with extensive consequences for the patient. The incidence of complications after median sternotomy is as high as 0.4-8 %. Wound and sternal dehiscence and a septic course with mediastinitis leading to septic shock is a feared complication with a high mortality next to the chronic course of the infection with the clinical correlation of presternal fistulas. An early diagnosis and surgical intervention is decisive to enhance the prognosis of the disease, leading to a significant increase in the survival rate of patients.

摘要

伴有胸骨骨髓炎的深部胸骨感染是罕见病症,会给患者带来严重后果。正中开胸术后并发症的发生率高达0.4 - 8%。伤口及胸骨裂开以及伴有纵隔炎导致感染性休克的脓毒症病程是令人恐惧的并发症,死亡率很高,仅次于伴有胸骨前瘘临床关联的慢性感染病程。早期诊断和手术干预对于改善疾病预后、显著提高患者生存率至关重要。

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1
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Int Wound J. 2024 Jan;21(1):e14349. doi: 10.1111/iwj.14349. Epub 2023 Aug 18.
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Microbiological study of sternal osteomyelitis after median thoracotomy - a retrospective cohort study.正中开胸术后胸骨骨髓炎的微生物学研究——回顾性队列研究。
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本文引用的文献

1
Deep sternal wound infections following open heart surgery in Iceland: a population-based study.冰岛心脏直视手术后的深部胸骨伤口感染:一项基于人群的研究。
Scand Cardiovasc J. 2008 Jun;42(3):208-13. doi: 10.1080/14017430801919557.
2
Deep sternal wound infection requiring revision surgery: impact on mid-term survival following cardiac surgery.需要翻修手术的深部胸骨伤口感染:对心脏手术后中期生存的影响。
Eur J Cardiothorac Surg. 2008 Apr;33(4):673-8. doi: 10.1016/j.ejcts.2008.01.002. Epub 2008 Feb 19.
3
Superficial and deep sternal wound infection after more than 9000 coronary artery bypass graft (CABG): incidence, risk factors and mortality.
自体肌皮瓣植入治疗慢性难治性感染性胸壁窦道:一例报告。
J Cardiothorac Surg. 2023 Apr 10;18(1):121. doi: 10.1186/s13019-023-02205-5.
4
[Sternal osteomyelitis - Surgical treatment concepts].[胸骨骨髓炎 - 外科治疗理念]
Chirurg. 2016 Jun;87(6):537-50. doi: 10.1007/s00104-016-0218-x.
5
[Surgical reconstructive procedures of the chest wall after mediastinitis].[纵隔炎后胸壁的外科重建手术]
Chirurg. 2016 Jun;87(6):489-96. doi: 10.1007/s00104-016-0173-6.
9000余例冠状动脉旁路移植术(CABG)后表浅及深部胸骨伤口感染:发生率、危险因素及死亡率
BMC Infect Dis. 2007 Sep 23;7:112. doi: 10.1186/1471-2334-7-112.
4
Staphylococcal post-sternotomy mediastinitis: five year audit.金黄色葡萄球菌性开胸术后纵隔炎:五年审计
ANZ J Surg. 2005 Apr;75(4):198-203. doi: 10.1111/j.1445-2197.2005.03371.x.
5
Multivariate analysis of risk factors for deep and superficial sternal infection after coronary artery bypass grafting at a tertiary care medical center.在一家三级医疗中心对冠状动脉搭桥术后深部和表浅胸骨感染危险因素的多变量分析。
Semin Thorac Cardiovasc Surg. 2004 Spring;16(1):53-61. doi: 10.1053/j.semtcvs.2004.01.009.
6
Risk factors for mediastinitis after cardiac surgery.心脏手术后纵隔炎的危险因素。
Ann Thorac Surg. 2004 Feb;77(2):676-83. doi: 10.1016/S0003-4975(03)01523-6.
7
The median sternal incision in intracardiac surgery with extracorporeal circulation; a general evaluation of its use in heart surgery.体外循环下心内手术的正中胸骨切口;对其在心脏手术中应用的综合评估。
Surgery. 1957 Oct;42(4):753-61.
8
Disruption and infection of median sternotomy: a comprehensive review.正中胸骨切开术的中断与感染:一项全面综述
Eur J Cardiothorac Surg. 2002 May;21(5):831-9. doi: 10.1016/s1010-7940(02)00124-0.
9
Postoperative mediastinitis in cardiac surgery - microbiology and pathogenesis.心脏手术术后纵隔炎——微生物学与发病机制
Eur J Cardiothorac Surg. 2002 May;21(5):825-30. doi: 10.1016/s1010-7940(02)00084-2.
10
Diagnostic validity of computed tomography for mediastinitis after cardiac surgery.心脏手术后纵隔炎的计算机断层扫描诊断有效性
Ann Thorac Cardiovasc Surg. 2001 Apr;7(2):94-8.