Vadacca Marta, Bruni Rosa, Terminio Nicolò, Sambataro Gianluca, Margiotta Domenico, Serino Francesco Maria, Afeltra Antonella
Campus Bio Medico, Via Alvaro del Portillo 200, 00128, Rome, Italy,
Clin Rheumatol. 2014;33(10):1443-50. doi: 10.1007/s10067-014-2593-3. Epub 2014 Apr 11.
This prospective study aims to examine alexithymia, mood states and pain experience in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) patients. We enrolled 49 patients with SLE or RA. All patients were evaluated through a set of questionnaires: (1) the Toronto Alexithymia Scale-20 (TAS), (2) the Profile of Mood States (POMS) and (3) visual analogue scale (VAS) and Questionario Italiano sul Dolore, self-report measures to assess pain intensity. Alexithymia was more prevalent in RA (44 %) than in SLE (37.5 %). The mean values of VAS were significantly higher in RA than in SLE population (p < 0.05). A linear relation between TAS and VAS values has been found in SLE (R = 0.714, p < 0.0001). The mean values of POMS regarding all negative dimensions of mood were higher in SLE than in RA. There was a linear relationship between TAS and POMS values in SLE patients (R = 0.7, p < 0.001). We found a high prevalence of alexithymia in SLE and RA. The chronic pain is influenced by emotional status as documented by a linear relation between TAS and VAS values in SLE patients. The difficulty in reporting emotional responses in these patients seems to be mediated by negative mood states.
这项前瞻性研究旨在调查系统性红斑狼疮（SLE）和类风湿关节炎（RA）患者的述情障碍、情绪状态及疼痛体验。我们招募了49例SLE或RA患者。所有患者均通过一系列问卷进行评估：（1）多伦多述情障碍量表-20（TAS），（2）情绪状态剖面图（POMS），以及（3）视觉模拟量表（VAS）和意大利语疼痛问卷，这些均为评估疼痛强度的自我报告测量工具。RA患者中述情障碍的患病率（44%）高于SLE患者（37.5%）。RA患者的VAS平均值显著高于SLE患者（p<0.05）。在SLE患者中发现TAS值与VAS值之间存在线性关系（R=0.714，p<0.0001）。SLE患者在情绪所有消极维度方面的POMS平均值高于RA患者。SLE患者中TAS值与POMS值之间存在线性关系（R=0.7，p<0.001）。我们发现SLE和RA患者中述情障碍的患病率较高。如SLE患者中TAS值与VAS值之间的线性关系所示，慢性疼痛受情绪状态的影响。这些患者在表达情绪反应方面的困难似乎由消极情绪状态介导。
