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抗菌肥皂的最新情况:美国食品药品监督管理局重新审视三氯生。

Update on antibacterial soaps: the FDA takes a second look at triclosans.

作者信息

Bergstrom Kendra Gail

出版信息

J Drugs Dermatol. 2014 Apr;13(4):501-3.

Abstract

In December of 2013 the Food and Drug Administration announced it would look further into the safety and efficacy of the biocide triclosan and requested further safety data as part of a new review with the Environmental Protection Agency. The use of triclosan has increased exponentially since its introduction in in 1972, to the point that 75% of commercial soap brands contain triclosan and 76% of a nationwide sample of adults and children excrete triclosan in the urine. This announcement raised an important dialog about the appropriate use of all over the counter biocides. Particular concerns include whether these biocides are more effective than regular soaps, whether they may create new drug resistant bacteria, and whether they may also act as hormone disruptors in humans or the environment.

摘要

2013年12月,美国食品药品监督管理局宣布将进一步调查杀菌剂三氯生的安全性和有效性,并要求提供更多安全数据,作为与环境保护局进行新审查的一部分。自1972年引入以来,三氯生的使用呈指数级增长,以至于75%的商业肥皂品牌含有三氯生,在全国范围内的成年人和儿童样本中,76%的人尿液中排出三氯生。这一宣布引发了一场关于非处方杀菌剂合理使用的重要讨论。特别令人担忧的问题包括这些杀菌剂是否比普通肥皂更有效,它们是否会产生新的耐药细菌,以及它们是否也可能在人类或环境中充当激素干扰物。

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