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[腮腺炎再次感染的发生率及临床特征]

[Rate and clinical characteristics of mumps reinfection].

作者信息

Hatanaka Akio, Tateishi Yumiko, Honda Keiji, Kamada Tomoko, Tasaki Akihisa, Kishine Naomi, Takeda Takamori, Kawashima Yoshiyuki

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 2014 Feb;117(2):111-5. doi: 10.3950/jibiinkoka.117.111.

DOI:10.3950/jibiinkoka.117.111
PMID:24720158
Abstract

Mumps infection is anecdotally believed to occur only once over a lifetime. However, in recent years, it has gradually come to be recognized among pediatricians that mumps reinfection is not a rare condition, and some criteria for the mumps reinfection have been proposed. One of the widely accepted criteria is levels higher than 25.8 IU/dl of serum IgG antibodies against the mumps virus and lower than 2.0 IU/dl of serum IgM antibodies. From July 2010 to June 2011, 45 patients with acute swelling of the major salivary gland(s) were enrolled into our survey of mumps reinfection in Tsuchiura Kyodo General hospital. Serum IgG and IgM antibodies against the mumps virus were measured at the initial visit. Ten cases were diagnosed as having primary infection with the mumps virus, while the other 10 cases were diagnosed as having reinfection with the mumps virus according to the criteria. The present study suggests that mumps reinfection is a common condition in patients with acute swelling of the major salivary glands in adulthood.

摘要

据坊间传闻,腮腺炎感染一生仅发生一次。然而,近年来儿科医生逐渐认识到腮腺炎再次感染并非罕见情况,并且已经提出了一些腮腺炎再次感染的标准。其中一个被广泛接受的标准是抗腮腺炎病毒的血清IgG抗体水平高于25.8 IU/dl且血清IgM抗体水平低于2.0 IU/dl。2010年7月至2011年6月,土浦协同综合医院对45例主要唾液腺急性肿胀患者进行了腮腺炎再次感染调查。在初次就诊时测量了抗腮腺炎病毒的血清IgG和IgM抗体。10例被诊断为原发性腮腺炎病毒感染,而其他10例根据该标准被诊断为腮腺炎病毒再次感染。本研究表明,腮腺炎再次感染在成年期主要唾液腺急性肿胀患者中很常见。

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