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从富血小板血浆到反向假体:治疗肩袖病变的争议

From platelet-rich plasma to the reverse prosthesis: controversies in treating rotator cuff pathology.

作者信息

Craig Edward V, Galatz Leesa M, Sperling John W

机构信息

Attending Surgeon, Department of Orthopedics, Hospital for Special Surgery, New York, New York.

出版信息

Instr Course Lect. 2014;63:63-70.

Abstract

Rotator cuff pathology and tearing remains a common cause of shoulder pain and disability. Although little controversy and disagreement exists regarding the treatment of small to moderate size tears in good quality tissue without retraction, there is difficulty in agreeing on the ideal treatment of the largest tears, particularly because those tears may be accompanied by widely variable levels of pain and function. Clinical decision making is made more difficult because of the variable presentations observed in patients with a documented full-thickness rotator cuff tear: some have good function and no pain, some have good function and pain, some have poor function and no pain, and some have both poor function and pain. The role of biologics as an adjunct in treating most rotator cuff tears remains unclear, with ongoing exploration of the roles of stem cells, growth factors, and platelet-rich plasma. In patients with unreconstructable tears with marked weakness in external rotation but good elevation, a latissimus transfer may restore rotation. Patches may play a role in partial repairs while serving as both a lattice for healing and a biomechanical anchoring point for sutures. In patients with massive tears and arthritis and in many who have rotator cuff insufficiency, pseudoparalysis, or anterosuperior escape without arthritis, reverse shoulder arthroplasty has led to improvements in pain and strength and revolutionized the treatment of rotator cuff tears.

摘要

肩袖病变和撕裂仍然是肩部疼痛和功能障碍的常见原因。尽管对于质量良好且无回缩的中小尺寸撕裂的治疗几乎没有争议,但对于最大撕裂的理想治疗方法难以达成共识,特别是因为这些撕裂可能伴有程度广泛不同的疼痛和功能障碍。由于在记录为全层肩袖撕裂的患者中观察到的表现各异,临床决策变得更加困难:一些患者功能良好且无疼痛,一些患者功能良好但有疼痛,一些患者功能差但无疼痛,还有一些患者功能差且有疼痛。生物制剂作为治疗大多数肩袖撕裂的辅助手段的作用仍不明确,目前正在探索干细胞、生长因子和富血小板血浆的作用。对于那些无法重建且外旋明显无力但抬高良好的撕裂患者,背阔肌转移术可能恢复旋转功能。补片在部分修复中可能发挥作用,它既是愈合的支架,也是缝线的生物力学锚定点。对于有巨大撕裂和关节炎的患者以及许多肩袖功能不全、假性麻痹或无前关节炎的前上脱位患者,反式肩关节置换术已使疼痛和力量得到改善,并彻底改变了肩袖撕裂的治疗方法。

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