Nakajima Y, Shibayama T, Yamamoto H, Suzuki Y, Matsuoka K, Kaneda S
Department of Urology, Saiseikai Central Hospital.
Hinyokika Kiyo. 1989 Apr;35(4):623-30.
The usefulness of a chemical prosthesis was studied for the diagnosis and treatment of 20 patients with erectile impotence (14 due to diabetes, 2 due to pelvic surgery and 4 due to psychogenic factors) using papaverine hydrochloride and phentolamine mesilate. Absolute erection was observed in 16 patients (80%) and coital penetration was possible in all 9 patients who actually tried sexual intercourse. Penile arterial blood flow was measured in 15 patients using a real-time mechanical sector duplex scanner (Diasonics DRF/400V) just before and after the chemical prosthesis, and a marked increase in blood flow was observed in all patients after administration. From these results, it is considered that measurement of the penile blood flow using a mechanical sector duplex scanner is useful in the diagnosis and monitoring of impotence. Furthermore, a chemical prosthesis is suitable mainly for the treatment of impotence due to diabetes, by adjusting the dosage and administration.
使用盐酸罂粟碱和甲磺酸酚妥拉明对20例勃起功能障碍患者（14例因糖尿病、2例因盆腔手术、4例因心理因素）进行化学假体诊断和治疗的有效性进行了研究。16例患者（80%）出现完全勃起，所有实际尝试性交的9例患者均能进行性交插入。在15例患者中，使用实时机械扇形双功扫描仪（Diasonics DRF/400V）在化学假体治疗前后测量阴茎动脉血流，给药后所有患者血流均显著增加。根据这些结果，认为使用机械扇形双功扫描仪测量阴茎血流对勃起功能障碍的诊断和监测有用。此外，通过调整剂量和给药方式，化学假体主要适用于糖尿病所致勃起功能障碍的治疗。
