钙信号和内质网动力学在海洋原口动物门纽形动物门的受精过程中的作用。

Calcium signaling and endoplasmic reticulum dynamics during fertilization in marine protostome worms belonging to the phylum Nemertea.

机构信息

Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA.

出版信息

Biochem Biophys Res Commun. 2014 Aug 1;450(3):1182-7. doi: 10.1016/j.bbrc.2014.03.156. Epub 2014 Apr 8.

DOI:10.1016/j.bbrc.2014.03.156

Abstract

Metaphase-I-arrested eggs of marine protostome worms in the phylum Nemertea generate a series of point-source calcium waves during fertilization. Such calcium oscillations depend on inositol-1,4,5-trisphosphate-mediated calcium release from endoplasmic reticulum (ER) stores that undergo structural reorganizations prior to and after fertilization. This article reviews fertilization-induced calcium transients and ER dynamics in nemertean eggs and compares these topics to what has been reported for other animals in order to identify unifying characteristics and distinguishing features of calcium responses during fertilization across the animal kingdom.

摘要

海洋原口动物门 Nemertea 门的有丝分裂 I 期被阻止的卵在受精过程中会产生一系列点状钙波。这种钙振荡依赖于肌醇 1,4,5-三磷酸介导的内质网 (ER) 储存钙释放，这种释放会在受精前后发生结构重排。本文综述了 nemertean 卵中受精诱导的钙瞬变和 ER 动力学，并将这些主题与其他动物的报道进行了比较，以确定动物王国受精过程中钙反应的统一特征和区别特征。