Löhr H F, Ramadori G, Mayet W J, Hess G, Meyer zum Büschenfelde K H
I. Medizinische Klinik und Poliklinik der Universität Mainz.
Dtsch Med Wochenschr. 1989 Jul 7;114(27):1069-72. doi: 10.1055/s-2008-1066718.
A lambda-light chain-IgA plasmocytoma, accompanied by a changing clinical picture of fever, nocturnal perspirations and weight loss, developed in a 46-year-old homosexual male with AIDS, stage IV (classification according to the Centers for Disease Control). He had been suffering from recurrent Salmonella septicaemia. Serum protein electrophoresis demonstrated marked elevation of the beta- and gamma-fractions (44% and 24%, respectively). There were 15% plasma cells in the differential blood count and in the bone marrow smear. Immunoelectrophoresis demonstrated free lambda-light chains. The IgA concentration in cerebrospinal fluid was raised to 202 mg/l, and there was an IgA paraproteinaemia. The patient died during a recurrence of the Salmonella septicaemia from septic cardiovascular failure.
一名46岁患有艾滋病IV期（根据疾病控制中心分类）的同性恋男性出现了λ轻链-IgA浆细胞瘤，伴有发热、夜间盗汗和体重减轻等不断变化的临床症状。他曾反复发生沙门氏菌败血症。血清蛋白电泳显示β和γ组分显著升高（分别为44%和24%）。血常规分类和骨髓涂片中有15%的浆细胞。免疫电泳显示游离λ轻链。脑脊液中IgA浓度升高至202mg/l，存在IgA副蛋白血症。患者在沙门氏菌败血症复发期间死于感染性心血管衰竭。
