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一对致细胞病变/非致细胞病变边境病病毒的全基因组序列

Complete genome sequences of a cytopathic/noncytopathic pair of border disease viruses.

作者信息

Neill John D, Ridpath Julia F

机构信息

Ruminant Diseases and Immunology Research Unit, National Animal Disease Center, U.S. Department of Agriculture, ARS, Ames, Iowa, USA.

出版信息

Genome Announc. 2014 Apr 10;2(2):e00260-14. doi: 10.1128/genomeA.00260-14.

Abstract

The complete genome sequences of a cytopathic/noncytopathic pair of border disease viruses (BDV) that were isolated from a sheep with mucosal disease-like lesions were determined. The cytopathic virus possessed an insert of 288 nucleotides that was derived from the Jiv cellular transcript and had 37 nucleotide differences from the noncytopathic virus.

摘要

从一只患有黏膜病样病变的绵羊中分离出一对细胞病变/非细胞病变的边界病病毒(BDV),并测定了它们的全基因组序列。细胞病变病毒含有一段288个核苷酸的插入片段,该片段来源于Jiv细胞转录本,与非细胞病变病毒有37个核苷酸差异。

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