Lasters F, Mallegho C, Boudewyns A, Vanderveken O, Cox T, Ketelslagers K, Verbraecken J
Acta Clin Belg. 2014 Apr;69(2):87-91. doi: 10.1179/0001551214Z.00000000028. Epub 2014 Mar 4.
Continuous positive airway pressure (CPAP) is the first line treatment for moderate to severe obstructive sleep apnea syndrome. Despite the high effectiveness of this treatment, its use is often limited by suboptimal compliance and/or intolerance. Nasal side effects are considered a major cause of low therapeutic compliance. At present, there are no data to predict which patients will develop CPAP intolerance caused by nasal symptoms and only few studies looked at the effect of treatment of nasal symptoms on CPAP compliance. The first section of this review focuses on the impact of nasal symptoms (pre-existing or as a side effect of CPAP) on CPAP compliance/intolerance. The second section deals with the effect of nasal symptom treatment on CPAP compliance.
持续气道正压通气（CPAP）是中重度阻塞性睡眠呼吸暂停综合征的一线治疗方法。尽管这种治疗方法疗效显著，但其应用常常受到依从性欠佳和/或不耐受的限制。鼻部副作用被认为是治疗依从性低的主要原因。目前，尚无数据能够预测哪些患者会因鼻部症状而出现CPAP不耐受，仅有少数研究关注了鼻部症状治疗对CPAP依从性的影响。本综述的第一部分聚焦于鼻部症状（既往存在的或作为CPAP的副作用）对CPAP依从性/不耐受的影响。第二部分探讨了鼻部症状治疗对CPAP依从性的作用。
