Yamamoto E, Miyakawa A, Hiratsuka H, Kumagai S, Kohama G
Dept. of Oral Surgery, School of Med., Kanazawa Univ.
Gan No Rinsho. 1989 Jun;35(7):815-24.
A secondary metastasis after surgery was uncovered in 12 out of 73 cases of oral squamous cancer. The clinical and histological characteristic tendencies of the metastasis of these 12 cases were the tongue as the tumor site (11/12), and an aggressive invasion in the tumor-host borderline with 2 of Gr, 3, 5 of Gr. 4C and 5 of Gr. 4D, according to the grading of Yamamoto and Kohama (1982). The control of these metastases was not easy because of their multiple and extra-nodal spread. Tumor-free survival occurred in 4 out of 11 (36.3%). Therefore, in some situations, a prophylactic neck dissection would seem to be recommended.
在73例口腔鳞状癌患者中,有12例在术后发现了继发性转移。这12例转移病例的临床和组织学特征倾向为:肿瘤部位为舌(11/12),根据山本和小滨(1982年)的分级,肿瘤与宿主边界处侵袭性强,其中2级为Gr. 3,5级为Gr. 4C,5级为Gr. 4D。由于这些转移具有多发性和结外扩散,因此对其进行控制并不容易。11例中有4例(36.3%)实现了无瘤生存。因此,在某些情况下,似乎建议进行预防性颈清扫术。