Egorova S G, Kokhanova I D, Rudinskaia T D, Sorkin E E
Ontogenez. 1989 Mar-Apr;20(2):209-15.
A new antigen of mammary tumor cells has been revealed using monoclonal antibodies. A similar antigen was detected also in certain types of secretory epithelia of oesophagus, stomach, salivary gland, and embryonic large intestine. Upon malignization, antigen persists in invasive ductal cancer of mammary gland and is expressed in cancers of ovary and rectum. The molecular weight of the antigen is greater than 2,000 kD.
利用单克隆抗体揭示了一种乳腺肿瘤细胞的新抗原。在食管、胃、唾液腺和胚胎大肠的某些类型分泌上皮中也检测到了类似抗原。恶变时,该抗原在乳腺浸润性导管癌中持续存在,并在卵巢癌和直肠癌中表达。该抗原的分子量大于2000 kD。