Capparelli R, Iannelli D
Department of Animal Production, University of Naples, Italy.
Hybridoma. 1989 Jun;8(3):315-21. doi: 10.1089/hyb.1989.8.315.
A monoclonal antibody against goat immunoglobulins recognizes an allotypic determinant (A1) which is common to goat, sheep, cattle and water buffalo. The frequency of the corresponding gene (A') is about the same in all four species, indicating the existence of a polymorphism that remained stable over a period of about 18-20 million years.
一种抗山羊免疫球蛋白的单克隆抗体识别一种同种异型决定簇（A1），该决定簇在山羊、绵羊、牛和水牛中是共有的。相应基因（A'）在所有这四个物种中的频率大致相同，这表明存在一种在大约1800万至2000万年的时间里保持稳定的多态性。
