评估补充阿维巴坦的联合纸片法检测产OXA-48碳青霉烯酶肠杆菌科细菌的效果。
Evaluation of avibactam-supplemented combination disk tests for the detection of OXA-48 carbapenemase-producing Enterobacteriaceae.
作者信息
Huang Te-Din, Berhin Catherine, Bogaerts Pierre, Glupczynski Youri
机构信息
National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-negative bacteria, CHU Dinant-Godinne|UCL Namur, 1 Avenue Dr. G. Therasse, 5530 Yvoir, Belgium.
National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-negative bacteria, CHU Dinant-Godinne|UCL Namur, 1 Avenue Dr. G. Therasse, 5530 Yvoir, Belgium.
出版信息
Diagn Microbiol Infect Dis. 2014 Jun;79(2):252-4. doi: 10.1016/j.diagmicrobio.2014.03.010. Epub 2014 Mar 18.
The ability of various combination disk tests (CDTs) incorporating avibactam to detect OXA-48 carbapenemase-producing Enterobacteriaceae was evaluated. The CDT using 30-μg temocillin alone and supplemented with 5-μg avibactam showed good performance and could be an adjunctive test to the classic CDT containing class A and class B carbapenemase inhibitors for the positive discrimination of OXA-48 carbapenemase producers from carbapenemase-negative strains.
评估了包含阿维巴坦的各种联合药敏试验（CDT）检测产OXA-48碳青霉烯酶肠杆菌科细菌的能力。单独使用30μg替莫西林并补充5μg阿维巴坦的CDT表现良好，对于从碳青霉烯酶阴性菌株中阳性鉴别出产OXA-48碳青霉烯酶的菌株而言，它可以作为包含A类和B类碳青霉烯酶抑制剂的经典CDT的辅助试验。
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