Machado-Rodrigues Aristides M, Leite Neiva, Coelho e Silva Manuel J, Valente-dos-Santos João, Martins Raul A, Mascarenhas Luis P G, Boguszewski Margaret C S, Padez Cristina, Malina Robert M
Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal.
J Phys Act Health. 2015 Jan;12(1):13-9. doi: 10.1123/jpah.2013-0053. Epub 2014 Apr 11.
Associations of metabolic syndrome (MetS) with lifestyle behaviors in youth is potentially important for identifying subgroups at risk and encourage interventions. This study evaluates the associations among the clustering of metabolic risk factors and moderate-to-vigorous physical activity (MVPA) in youth.
The sample comprised 522 girls and 402 boys (N = 924) aged 11 to 17 years. Height, weight, waist circumference (WC), fasting glucose, high-density lipoprotein cholesterol, triglycerides, and blood pressures were measured. Cardiorespiratory fitness (CRF) was assessed using the 20-m shuttle run test. MVPA was estimated with a 3-day diary. Outcome variables were statistically normalized and expressed as z scores. A clustered metabolic risk score was computed as the mean of z scores. Multiple linear regression was used to test associations between metabolic risk and MVPA by sex, adjusted for age, WC, and CRF.
After adjustment for potential confounders, MVPA was inversely associated with the clustering of metabolic risk factors in girls, but not in boys; in addition, after adjusting for WC, the statistical model of that relationship was substantially improved in girls.
MVPA was independently associated with increased risk of MetS in girls. Additional efforts are needed to encourage research with different analytical approach and standardization of criteria for MetS in youth.
代谢综合征（MetS）与青少年生活方式行为之间的关联对于识别高危亚组和促进干预措施具有潜在重要意义。本研究评估了青少年代谢危险因素聚集与中等到剧烈身体活动（MVPA）之间的关联。
样本包括522名女孩和402名男孩（N = 924），年龄在11至17岁之间。测量身高、体重、腰围（WC）、空腹血糖、高密度脂蛋白胆固醇、甘油三酯和血压。使用20米往返跑测试评估心肺适能（CRF）。通过3天的日记估计MVPA。将结果变量进行统计标准化并表示为z分数。计算聚类代谢风险评分作为z分数的平均值。采用多元线性回归按性别检验代谢风险与MVPA之间的关联，并对年龄、WC和CRF进行校正。
在对潜在混杂因素进行校正后，MVPA与女孩代谢危险因素的聚集呈负相关，但与男孩无关；此外，在校正WC后，女孩中该关系的统计模型有显著改善。
MVPA与女孩患MetS风险增加独立相关。需要进一步努力鼓励采用不同分析方法的研究以及青少年MetS标准的标准化。
