三倍体胎儿：评估孕妇血清甲胎蛋白水平极高时的一项重要考量因素。
Triploid fetus: an important consideration in the evaluation of very high maternal serum alpha-fetoprotein.
作者信息
Kazazian L C, Baramki T A, Thomas R L
机构信息
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
出版信息
Prenat Diagn. 1989 Jan;9(1):27-30. doi: 10.1002/pd.1970090105.
Two patients referred for evaluation of very high maternal serum alpha-fetoprotein (10-20 multiples of the median) were carrying triploid fetuses with placentas showing features of partial hydatidiform mole. The diagnosis of fetal triploidy should be considered when there is a very high maternal serum alpha-fetoprotein and no ultrasound evidence of open neural tube defect, ventral wall defect, or any other explanation. Therefore, chromosomal analysis of amniotic fluid cells in such cases is essential.
两名因母体血清甲胎蛋白水平极高（中位数的10 - 20倍）前来评估的患者怀有三倍体胎儿，其胎盘呈现部分性葡萄胎的特征。当母体血清甲胎蛋白水平极高且超声检查未发现开放性神经管缺陷、腹壁缺陷或任何其他解释时，应考虑胎儿三倍体的诊断。因此，在此类病例中对羊水细胞进行染色体分析至关重要。
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