Sigler Eric J, Randolph John C, Calzada Jorge I
*Division of Retina and Vitreous, Ophthalmic Consultants of Long Island, Lynbrook, New York; †Division of Vitreoretinal Surgery, Charles Retina Institute, Memphis, Tennessee; and ‡Division of Retina and Vitreous, Department of Ophthalmology, University of Tennessee School of Medicine, Memphis, Tennessee.
Retina. 2014 Aug;34(8):1651-7. doi: 10.1097/IAE.0000000000000138.
To compare the spectral-domain optical coherence tomography morphologic features and visual characteristics of a series of patients with epimacular membrane with and without a history of retinal breaks.
Prospective, comparative case series of patients with epimacular membrane. All patients were evaluated with spectral-domain optical coherence tomography and detailed peripheral retinal examination. Symptomatic patients were treated with pars plana vitrectomy and epimacular membrane removal based on standard visual criteria.
Macular proliferative vitreoretinopathy was present in 21 of 50 patients (42%). Approximately 18 of 21 patients had a previous retinal break, 5 of which were untreated before the initial examination. No retinal breaks were observed in the idiopathic group. Macular proliferative vitreoretinopathy was highly associated with a history of retinal breaks (P < 0.001). Presenting visual acuity was significantly worse (mean, 0.86 ± 0.44) for macular proliferative vitreoretinopathy than for the idiopathic group (mean, 0.44 ± 0.36).
Epimacular membrane occurring in the context of previous retinal breaks or macular proliferative vitreoretinopathy has a characteristic morphologic feature in spectral-domain optical coherence tomography. Surgical removal typically results in significant visual improvement.
比较一系列有或无视网膜裂孔病史的黄斑前膜患者的频域光学相干断层扫描形态学特征和视觉特性。
黄斑前膜患者的前瞻性、对比性病例系列研究。所有患者均接受频域光学相干断层扫描和详细的周边视网膜检查。有症状的患者根据标准视觉标准接受玻璃体切割术和黄斑前膜切除术治疗。
50例患者中有21例（42%）存在黄斑增殖性玻璃体视网膜病变。21例患者中约18例既往有视网膜裂孔，其中5例在初次检查前未接受治疗。特发性组未观察到视网膜裂孔。黄斑增殖性玻璃体视网膜病变与视网膜裂孔病史高度相关（P < 0.001）。黄斑增殖性玻璃体视网膜病变患者的初始视力（平均0.86±0.44）明显比特发性组（平均0.44±0.36）差。
既往有视网膜裂孔或黄斑增殖性玻璃体视网膜病变背景下出现的黄斑前膜在频域光学相干断层扫描中有特征性形态学特征。手术切除通常会使视力显著改善。
