聚赖氨酸诱导的双分子混合脂质膜中的相分离
Phase separation in bimolecular mixed lipid membranes induced by polylysine.
作者信息
Mittler-Neher S, Knoll W
机构信息
Max-Planck-Institut für Polymerforschung, Mainz, FRG.
出版信息
Biochem Biophys Res Commun. 1989 Jul 14;162(1):124-9. doi: 10.1016/0006-291x(89)91971-2.
PMID:2473744
Abstract
We demonstrate, for the first time, polylysine-induced phase separation in a bimolecular lipid membrane of a lecithin/phosphatidylglycerol-mixture by analysing the single channel current fluctuations of gramicidin. The bimodal conductance histograms are direct evidence for the incorporation of the transport system into the two coexisting phases of different composition.
摘要
我们首次通过分析短杆菌肽的单通道电流波动，证明了聚赖氨酸诱导卵磷脂/磷脂酰甘油混合物的双分子脂质膜发生相分离。双峰电导直方图是转运系统并入不同组成的两个共存相的直接证据。
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