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使用血小板生成素激动剂艾曲泊帕使狼疮相关血小板减少症患者的血小板计数成功恢复。

Successful platelet count recovery in lupus-associated thrombocytopenia with the thrombopoietin agonist eltrombopag.

作者信息

Scheinberg Phillip, Singulane Cristiane Carvalho, Barbosa Luis Sergio Guedes, Scheinberg Morton

机构信息

Hematology Service, Oncology Center, Hospital São José, Beneficência Portuguesa, São Paulo, Brazil.

出版信息

Clin Rheumatol. 2014 Sep;33(9):1347-9. doi: 10.1007/s10067-014-2600-8. Epub 2014 Apr 17.

Abstract

Eltrombopag is a new thrombomimetic medication approved for the treatment of immune thrombocytopenia. There are very few reports on the use of eltrombopag in patients with thrombocytopenia associated with sytemic lupus.We present a recent case of a patient with lupus with severe thrombocytopenia refractory to conventional therapy and full recovery with the use of eltrombopag. The present status of the literature with the use of this medication in patients with lupus is reviewed and discussed.

摘要

艾曲泊帕是一种新的拟血栓形成药物,已被批准用于治疗免疫性血小板减少症。关于艾曲泊帕在系统性红斑狼疮相关血小板减少症患者中的应用报道极少。我们报告了一例近期的狼疮患者病例,该患者严重血小板减少,对传统治疗无效,但使用艾曲泊帕后完全康复。本文对该药物在狼疮患者中的应用现状进行了综述和讨论。

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