Barriga José, Cerda Jaime, Abarca Katia, Ferrés Marcela, Fajuri Paula, Riquelme María, Carrillo Diego, Clavería Cristián
Rev Chilena Infectol. 2014 Feb;31(1):16-20. doi: 10.4067/S0716-10182014000100002.
Nosocomial infections generate high morbidity and mortality in children undergoing cardiac surgery.
To determine risk factors for nosocomial infections in children after congenital heart surgery.
A retrospective case-control study, in patients younger than 15 years undergoing surgery for congenital heart disease from January 2007 to December 2011 admitted to the Pediatric Critical Patient Unit (UPC-P) in a university hospital. For cases, the information was analyzed from the first episode of infection.
39 patients who develop infections and 39 controls who did not develop infection were enrolled. The median age of cases was 2 months. We identified a number of factors associated with the occurrence of infections, highlighting in univariate analysis: age, weight, univentricular heart physiology, complexity of the surgical procedure according to RACHS-1 and cardiopulmonary bypass (CPB) time ≥ 200 minutes. Multivariate analysis identified CPB time ≥ 200 minutes as the major risk factor, with an OR of 11.57 (CI: 1.04 to 128.5).
CPB time ≥ 200 minutes was the mayor risk factor associated with the development of nosocomial infections.
医院感染在接受心脏手术的儿童中会导致高发病率和死亡率。
确定先天性心脏病手术后儿童医院感染的危险因素。
一项回顾性病例对照研究，研究对象为2007年1月至2011年12月在一家大学医院儿科重症监护病房（UPC-P）接受先天性心脏病手术的15岁以下患者。对于病例，从首次感染发作时分析信息。
纳入了39例发生感染的患者和39例未发生感染的对照。病例的中位年龄为2个月。我们确定了一些与感染发生相关的因素，单因素分析中突出的因素有：年龄、体重、单心室心脏生理、根据RACHS-1分类的手术复杂性以及体外循环（CPB）时间≥200分钟。多因素分析确定CPB时间≥200分钟是主要危险因素，比值比为11.57（95%置信区间：1.04至128.5）。
CPB时间≥200分钟是与医院感染发生相关的主要危险因素。
