Effenberger Maria, Steinle Hartmut, Offner Felix A, Vogel Wolfgang, Millonig Gunda
aDepartment of Internal Medicine II, Gastroenterology and Hepatology, Medical University of Innsbruck, Innsbruck bDepartment of Pathology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria.
Eur J Gastroenterol Hepatol. 2014 Jun;26(6):676-8. doi: 10.1097/MEG.0000000000000050.
Gastritis cystica profunda (GCP) is a rare disease that shows multiple cystic gastric glands dispersed within the submucosa of the stomach. GCP occurs most commonly in patients who have undergone previous gastric surgery and presents as subepithelial tumor or a polypoid lesion. Here, we report the case of GCP in a 79-year-old patient who had undergone Billroth II gastric resection. During upper gastrointestinal endoscopy multiple lesions like tiny holes in the mucosa were observed. Endoscopic ultrasound showed cystic structures in the gastric submucosa. Biopsies finally proved the dispersed mucosal glands in the submucosa, which are pathognomonic for GCP. So far, in all published cases, GCP presented as polypoid lesions with no mucosal damage in upper gastrointestinal endoscopy. It is for the first time that GCP has been diagnosed with cystic lesions connected to the gastric lumen with a porus in each of the cysts.
胃深部囊肿性胃炎（GCP）是一种罕见疾病，表现为多个囊性胃腺散布于胃黏膜下层。GCP最常见于既往接受过胃部手术的患者，表现为上皮下肿瘤或息肉样病变。在此，我们报告一例79岁接受毕Ⅱ式胃切除术患者的GCP病例。上消化道内镜检查时观察到黏膜上有多个类似小孔的病变。内镜超声显示胃黏膜下层有囊性结构。活检最终证实黏膜下层有散在的黏膜腺，这是GCP的特征性表现。到目前为止，在所有已发表的病例中，GCP表现为息肉样病变，上消化道内镜检查时无黏膜损伤。GCP首次被诊断为与胃腔相连的囊性病变，每个囊肿都有一个小孔。
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