Konishi S, Song S Y, Ogawa T, Kanazawa I
Laboratory of Cellular Physiology, Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan.
Brain Res. 1989 Jun 19;490(1):162-5. doi: 10.1016/0006-8993(89)90444-7.
The actions of mammalian tachykinins on neurons of rat coeliac-superior mesenteric ganglia (C-SMG) were examined using intracellular recording in isolated preparations. Application of substance P, neurokinin A and neurokinin B produced fast and slow depolarizations in the ganglion cells. The two responses were clearly distinguishable in their electrophysiological characteristics. The results suggest that different receptor mechanisms are involved in fast and slow depolarizing actions of tachykinins in rat C-SMG cells.
利用离体标本的细胞内记录技术，研究了哺乳动物速激肽对大鼠腹腔 - 肠系膜上神经节（C - SMG）神经元的作用。施加P物质、神经激肽A和神经激肽B可使神经节细胞产生快速和缓慢的去极化。这两种反应在电生理特性上明显可区分。结果表明，不同的受体机制参与了速激肽对大鼠C - SMG细胞的快速和缓慢去极化作用。
