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恶性血液病患者的生育力保留治疗选择

Fertility-preserving treatment options in patients with malignant hematological diseases.

作者信息

Küçük Mert, Bolaman Ali Zahit, Yavaşoğlu Irfan, Kadıköylü Gürhan

机构信息

Adnan Menderes University, School of Medicine, Department of Obstetrics and Gynecology, Aydın, Turkey.

Adnan Menderes University, School of Medicine, Department of Internal Medicine, Division of Hematology, Aydın, Turkey.

出版信息

Turk J Haematol. 2012 Sep;29(3):207-16. doi: 10.5505/tjh.2012.72681. Epub 2012 Oct 5.

DOI:10.5505/tjh.2012.72681
PMID:24744663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3986744/
Abstract

The number of patients of reproductive age diagnosed with various malignant hematological diseases increases every year. These patients undergo chemotherapy, radiotherapy, and various other treatments that may have gonadotoxic effects. The life expectancy of these patients is increasing rapidly due to the variety of treatment options. As such, an increasing number of patients-as well as their parents and spouses-express their concerns about the patient's fertility post treatment. In the present review it was aimed to provide an overview of current fertility-preserving treatment options and the future of fertility preservation.

摘要

每年被诊断患有各种恶性血液病的育龄患者数量都在增加。这些患者接受化疗、放疗和其他可能具有性腺毒性作用的治疗。由于治疗选择的多样性,这些患者的预期寿命正在迅速提高。因此,越来越多的患者以及他们的父母和配偶表达了对患者治疗后生育能力的担忧。在本综述中,旨在概述当前的生育力保存治疗选择以及生育力保存的未来。

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引用本文的文献

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[Fertility analyses of patients with hematologic diseases after allogeneic hematopoietic stem cell transplantation].[异基因造血干细胞移植后血液病患者的生育力分析]
Zhonghua Xue Ye Xue Za Zhi. 2019 Jul 14;40(7):605-607. doi: 10.3760/cma.j.issn.0253-2727.2019.07.014.
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Reproductive issues in patients undergoing Hematopoietic Stem Cell Transplantation: an update.造血干细胞移植患者的生殖问题:最新进展
J Ovarian Res. 2016 Nov 1;9(1):72. doi: 10.1186/s13048-016-0279-y.
3
Knowledge, attitudes, and practices of hematologists regarding fertility preservation in Turkey.土耳其血液学家对生育力保存的知识、态度和实践。
Turk J Haematol. 2013 Sep;30(3):269-74. doi: 10.4274/Tjh.2012.0015. Epub 2013 Sep 5.

本文引用的文献

1
Semen quality and fertility in adult long-term survivors of childhood acute lymphoblastic leukemia.儿童期急性淋巴细胞白血病成年长期幸存者的精液质量和生育力。
Fertil Steril. 2011 Oct;96(4):837-42. doi: 10.1016/j.fertnstert.2011.07.1147. Epub 2011 Aug 24.
2
Management of fertility in patients treated for Hodgkin's lymphoma.霍奇金淋巴瘤患者的生育力管理。
Haematologica. 2011 Nov;96(11):1692-9. doi: 10.3324/haematol.2011.045856. Epub 2011 Aug 9.
3
Fertility considerations and preservation in haemato-oncology patients undergoing treatment.血液肿瘤患者治疗过程中的生育力考虑和保存。
Br J Haematol. 2011 May;153(3):291-308. doi: 10.1111/j.1365-2141.2011.08629.x. Epub 2011 Mar 9.
4
Options of fertility preservation in female cancer patients.女性癌症患者的生育力保存选择。
Obstet Gynecol Surv. 2010 Aug;65(8):531-42. doi: 10.1097/OGX.0b013e3181f8c0aa.
5
Fertility preservation after chemotherapy for Hodgkin lymphoma.霍奇金淋巴瘤化疗后的生育力保存。
Hematol Oncol. 2010 Dec;28(4):168-79. doi: 10.1002/hon.939.
6
Ethical issues regarding fertility preservation in adolescents and children.青少年和儿童生育力保存的伦理问题。
Pediatr Blood Cancer. 2009 Aug;53(2):249-53. doi: 10.1002/pbc.21996.
7
Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients.放射治疗对女性癌症患者生育力、妊娠及新生儿结局的影响。
Int J Radiat Oncol Biol Phys. 2009 Apr 1;73(5):1304-12. doi: 10.1016/j.ijrobp.2008.12.016.
8
Fertility preservation medicine: a new field in the care of young cancer survivors.生育力保存医学:年轻癌症幸存者护理中的一个新领域。
Pediatr Blood Cancer. 2009 Aug;53(2):267-73. doi: 10.1002/pbc.22003.
9
Ovarian preservation by GnRH agonists during chemotherapy: a meta-analysis.GnRH激动剂在化疗期间对卵巢的保护作用:一项荟萃分析。
J Womens Health (Larchmt). 2009 Mar;18(3):311-9. doi: 10.1089/jwh.2008.0857.
10
[Capability of oocyte maturation in human cryopreserved ovarian tissue following xenografting].[异种移植后人冷冻卵巢组织中卵母细胞成熟的能力]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008 Oct;30(5):583-8.