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超声检查在登革热诊断与评估中的应用

Sonography in the diagnosis and assessment of dengue Fever.

作者信息

Santhosh V R, Patil Prashanth G, Srinath M G, Kumar Ashok, Jain Aditi, Archana M

机构信息

Department of Radio-Diagnosis, M. S. Ramaiah Medical College and Hospitals, Bengaluru, Karnataka, India.

出版信息

J Clin Imaging Sci. 2014 Mar 21;4:14. doi: 10.4103/2156-7514.129260. eCollection 2014.

Abstract

OBJECTIVE

The objective of the following study is to determine the use of ultrasound as an important adjunct to clinical and laboratory profile in diagnosing dengue fever and in predicting the severity of the disease by correlating imaging features with platelet count. The variation in sonographic features seen in patients from different age groups was also studied.

MATERIALS AND METHODS

This is a retrospective study. 96 patients who were serologically diagnosed as having dengue fever between April and August 2012 were referred for ultrasound scanning of the abdomen and thorax and the imaging findings were analyzed.

RESULTS

Out of 96 sero-positive dengue cases, 64 (66.7%) patients showed edematous gallbladder (GB) wall thickening, 62 (64.5%) patients showed ascites, 48 (50%) patients had pleural effusion, 17 (17.7%) patients had hepatomegaly, 16 (16.7%) patients had splenomegaly and in 17 (17.7%) patients ultrasound findings were normal. Edematous GB wall thickening, ascites and pleural effusion were the most common combination of findings in all age groups. Edematous GB wall thickening was seen in 97.8% of patients with platelet count of less than 40,000 along with ascites (86.9%) and pleural effusion (58.6%). In patients with platelet count between 40,000 and 80,000 ascites was more common than edematous GB wall thickening. Significantly no abnormal sonographic finding was detected in patient with platelet count more than 150,000.

CONCLUSION

Sonographic features of thickened GB wall, pleural effusion (bilateral or right side), ascites, hepatomegaly and splenomegaly should strongly favor the diagnosis of dengue fever in patients presenting with fever and associated symptoms, particularly during an epidemic. The degree of thrombocytopenia showed a significant direct relationship to abnormal ultrasound features.

摘要

目的

以下研究的目的是通过将影像学特征与血小板计数相关联,确定超声作为临床和实验室检查的重要辅助手段在诊断登革热及预测疾病严重程度方面的作用。同时还研究了不同年龄组患者超声特征的差异。

材料与方法

这是一项回顾性研究。对2012年4月至8月间血清学诊断为登革热的96例患者进行腹部和胸部超声扫描,并对影像学结果进行分析。

结果

在96例血清学阳性的登革热病例中,64例(66.7%)患者出现胆囊壁水肿增厚,62例(64.5%)患者出现腹水,48例(50%)患者有胸腔积液,17例(17.7%)患者肝肿大,16例(16.7%)患者脾肿大,17例(17.7%)患者超声检查结果正常。胆囊壁水肿增厚、腹水和胸腔积液是所有年龄组最常见的检查结果组合。血小板计数低于40,000的患者中,97.8%出现胆囊壁水肿增厚,同时伴有腹水(86.9%)和胸腔积液(58.6%)。血小板计数在40,000至80,000之间的患者中腹水比胆囊壁水肿增厚更常见。血小板计数超过150,000的患者未检测到明显异常超声检查结果。

结论

对于出现发热及相关症状的患者,尤其是在流行期间,胆囊壁增厚、胸腔积液(双侧或右侧)、腹水、肝肿大和脾肿大等超声特征强烈提示登革热的诊断。血小板减少程度与异常超声特征呈显著正相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c5/3988603/0136309dc691/JCIS-4-14-g001.jpg

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