Erturk Engin, Aydogdu Kaya Ferdane, Kutanis Dilek, Besir Ahmet, Akdogan Ali, Geze Sükran, Tugcugil Ersagun
Department of Anesthesiology and Intensive Care, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey.
Department of Anesthesiology and Intensive Care, Faculty of Medicine, Recep Tayyip Erdoğan University, 53100 Rize, Turkey.
Biomed Res Int. 2014;2014:673682. doi: 10.1155/2014/673682. Epub 2014 Mar 13.
The aim of this study is to investigate the effectiveness of preemptive thoracic epidural analgesia (TEA) comparing conventional postoperative epidural analgesia on thoracotomy.
Forty-four patients were randomized in to two groups (preemptive: Group P, control: Group C). Epidural catheter was inserted in all patients preoperatively. In Group P, epidural analgesic solution was administered as a bolus before the surgical incision and was continued until the end of the surgery. Postoperative patient controlled epidural analgesia infusion pumps were prepared for all patients. Respiratory rates (RR) were recorded. Patient's analgesia was evaluated with visual analog scale at rest (VASr) and coughing (VASc). Number of patient's demands from the pump, pump's delivery, and additional analgesic requirement were also recorded.
RR in Group C was higher than in Group P at postoperative 1st and 2nd hours. Both VASr and VASc scores in Group P were lower than in Group C at postoperative 1st, 2nd, and 4th hours. Patient's demand and pump's delivery count for bolus dose in Group P were lower than in Group C in all measurement times. Total analgesic requirements on postoperative 1st and 24th hours in Group P were lower than in Group C.
We consider that preemptive TEA may offer better analgesia after thoracotomy.
本研究旨在探讨预防性胸段硬膜外镇痛(TEA)与传统开胸术后硬膜外镇痛相比的有效性。
44例患者随机分为两组(预防性组:P组,对照组:C组)。所有患者术前均置入硬膜外导管。P组在手术切口前给予硬膜外镇痛溶液推注,并持续至手术结束。为所有患者准备术后患者自控硬膜外镇痛输注泵。记录呼吸频率(RR)。采用视觉模拟评分法评估患者静息时(VASr)和咳嗽时(VASc)的镇痛效果。记录患者对泵的需求次数、泵的给药量以及额外的镇痛需求。
术后第1小时和第2小时,C组的RR高于P组。术后第1小时、第2小时和第4小时,P组的VASr和VASc评分均低于C组。在所有测量时间点,P组患者对推注剂量的需求和泵的给药次数均低于C组。P组术后第1小时和第24小时的总镇痛需求量低于C组。
我们认为预防性TEA可能在开胸术后提供更好的镇痛效果。