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奥维耶多地区孕妇的碘营养状况。是否需要补充碘?

Iodine nutrition in pregnant women from Oviedo area. Is iodine supplementation necessary?

作者信息

Menéndez Torre Edelmiro, Delgado Alvarez Elías, Rabal Artal Antonio, Suárez Gutiérrez Lorena, Rodríguez Caballero María Galiana, Ares Blanco Jessica, Díaz Naya Lucía, Fernández Fernández Juan Carlos

机构信息

Endocrinología y Nutrición, Hospital Universitario Central de Asturias, Oviedo, España.

Endocrinología y Nutrición, Hospital Universitario Central de Asturias, Oviedo, España.

出版信息

Endocrinol Nutr. 2014 Oct;61(8):404-9. doi: 10.1016/j.endonu.2014.02.005. Epub 2014 Apr 18.

DOI:10.1016/j.endonu.2014.02.005
PMID:24746240
Abstract

BACKGROUND AND OBJECTIVE

In Asturias, where iodine deficiency was eradicated in school children by the year 2000, iodine deficiency persisted in pregnant women, who were recommended to use of iodine supplementation. The aim of this study was to determine the iodine nutrition of pregnant women in our area and whether or not iodine supplements are needed.

MATERIAL AND METHODS

Throughout May and June 2013 we studied the iodine nutrition and thyroid function during the first trimester of pregnancy in 173 women in the health area of Oviedo.

RESULTS

The median urinary iodine was 197 μg/L. Iodinated supplements were used by 47% of women, which had a yoduria median higher than those not taking iodinated supplements (247 vs. 138 μg/L; p<.001), and also a higher TSH (2.30 vs 1.94 mU/L) although not significantly different. Yoduria was also higher in women who took more than 2 servings of dairy products (median: 230 μg/L) than those who took less (median: 191 μg/L). Within the group of women who were not taking iodine supplements, those regularly using iodized salt in the kitchen (47%) had a median urinary iodine concentration of 190μg/L indicating iodine sufficiency.

CONCLUSIONS

Iodinated supplements seem unnecessary nowadays in pregnant women of Oviedo who regularly take iodized salt and our recommendation in these cases should be to continue the use of iodized salt in the recommended amounts during pregnancy and consume at least two daily servings of milk or dairy products.

摘要

背景与目的

在阿斯图里亚斯地区,2000年学龄儿童碘缺乏问题已得到根除,但孕妇中碘缺乏现象依然存在,因此建议孕妇补充碘。本研究旨在确定我们地区孕妇的碘营养状况以及是否需要补充碘剂。

材料与方法

2013年5月至6月期间,我们对奥维耶多健康区的173名孕早期妇女的碘营养状况和甲状腺功能进行了研究。

结果

尿碘中位数为197μg/L。47%的妇女使用了含碘补充剂,其尿碘中位数高于未服用含碘补充剂的妇女(247 vs. 138μg/L;p<0.001),促甲状腺激素水平也更高(2.30 vs 1.94mU/L),不过差异不显著。摄入两份以上乳制品的妇女尿碘水平(中位数:230μg/L)也高于摄入量较少的妇女(中位数:191μg/L)。在未服用碘补充剂的妇女组中,经常在厨房使用加碘盐的妇女(47%)尿碘浓度中位数为190μg/L,表明碘充足。

结论

对于奥维耶多地区经常食用加碘盐的孕妇来说,目前似乎没有必要服用含碘补充剂,我们建议这些孕妇在孕期继续按推荐量食用加碘盐,并每天至少食用两份牛奶或乳制品。

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Iodine Supplementation in Mildly Iodine-Deficient Pregnant Women Does Not Improve Maternal Thyroid Function or Child Development: A Secondary Analysis of a Randomized Controlled Trial.轻度碘缺乏孕妇补充碘剂并不会改善母体甲状腺功能或儿童发育:一项随机对照试验的二次分析。
Front Endocrinol (Lausanne). 2020 Oct 6;11:572984. doi: 10.3389/fendo.2020.572984. eCollection 2020.
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Nutrients. 2020 Aug 31;12(9):2656. doi: 10.3390/nu12092656.
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Endocr Connect. 2018 May;7(5):762-767. doi: 10.1530/EC-18-0131. Epub 2018 Apr 26.