Gutiérrez-González E, Batalla A, de la Mano D
Hospital San Agustín, Avilés (Asturias), Spain.
Dermatol Online J. 2014 Apr 16;20(4):22338.
The development of lentigines in areas previously involved by psoriasis has been reported in the literature, classically related to phototherapy but also to topical products. More recently, some authors have described several cases of lentigines appearing in resolving psoriatic plaques during or after treatment with anti-tumour necrosis factor (TNF) drugs used to treat severe plaque psoriasis, including adalimumab, etanercept, and infliximab. We report the case of a patient that developed multiple lentigines after clearance of the plaques of psoriasis receiving treatment with ustekinumab for his psoriasis.
文献中曾报道过银屑病既往受累区域出现雀斑样痣，经典情况与光疗有关，但也与局部用药有关。最近，一些作者描述了几例在使用抗肿瘤坏死因子（TNF）药物治疗重度斑块状银屑病（包括阿达木单抗、依那西普和英夫利昔单抗）期间或之后，在银屑病斑块消退过程中出现雀斑样痣的病例。我们报告了1例接受乌司奴单抗治疗银屑病的患者，在银屑病斑块清除后出现了多发性雀斑样痣。
