Bravo Erick A, Carrion Leonidas, Paucar Silvia M, Mendoza Rossana, Rivera Carlos
Universidad Nacional Mayor de San Marcos, Hospital Nacional "Luis N. Saenz".
Dermatol Online J. 2014 Apr 16;20(4):22374.
Pityriasis Rubra Pilaris (PRP) is an uncommon skin disorder characterized by follicular keratosis, palmoplantar keratoderma, and erythroderma. The traditional preferred treatment is oral retinoids, but over the last decade, biologic therapy with anti-TNF agents has been used with success. We report the case of a 51 year- old man with a clinical and histopathological diagnosis of PRP. He underwent therapy with adalimumab and showed clearance of skin lesions within the fourth week of treatment.
红皮病型毛发红糠疹（PRP）是一种罕见的皮肤疾病，其特征为毛囊角化、掌跖角化和红皮病。传统的首选治疗方法是口服维甲酸类药物，但在过去十年中，使用抗TNF药物的生物疗法已取得成功。我们报告一例51岁男性患者，临床和组织病理学诊断为PRP。他接受了阿达木单抗治疗，在治疗的第四周内皮肤病变消退。
