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牙科研究中的统计学基础:第二部分。

Primer of statistics in dental research: Part II.

作者信息

Shintani Ayumi

机构信息

Department of Clinical Epidemiology and Biostatistics, Osaka University, Japan.

出版信息

J Prosthodont Res. 2014 Apr;58(2):85-91. doi: 10.1016/j.jpor.2014.03.003. Epub 2014 Apr 17.

Abstract

The Part I of Primer of Statistics in Dental Research covered five topics that are often mentioned in statistical check list of many peer-review journals including (1) statistical graph, (2) how to deal with outliers, (3) p-value and confidence interval, (4) testing equivalence, and (5) multiplicity Adjustment. The Part II of the series covers another set of important topics in dental statistics including (1) selecting the proper statistical tests, (2) repeated measures analysis, (3) epidemiological consideration for causal association, and (4) analysis of agreement. First, a guide in selecting the proper statistical tests based on the research question will be laid out in text and with a table so that researchers choose the univariable statistical test by answering five simple questions. Second, the importance of utilizing repeated measures analysis will be illustrated. This is a key component of data analysis as in many dental studies, observations are considered repeated in a single patient (several teeth are measured in a single patient). Third, concepts of confounding and the use of regression analysis are explained by going over a famous observational cohort study. Lastly, the use of proper agreement analysis vs. correlation for study of agreement will be discussed to avoid a common pitfall in dental research.

摘要

《牙科研究统计学基础》第一部分涵盖了许多同行评审期刊统计检查清单中经常提到的五个主题,包括:(1)统计图;(2)如何处理异常值;(3)p值和置信区间;(4)等效性检验;(5)多重性调整。该系列的第二部分涵盖了牙科统计学中的另一组重要主题,包括:(1)选择合适的统计检验;(2)重复测量分析;(3)因果关联的流行病学考量;(4)一致性分析。首先,将通过文字和表格阐述根据研究问题选择合适统计检验的指南,以便研究人员通过回答五个简单问题来选择单变量统计检验。其次,将说明使用重复测量分析的重要性。这是数据分析的关键组成部分,因为在许多牙科研究中,单个患者的观察结果被视为重复测量(在单个患者中测量多颗牙齿)。第三,通过回顾一项著名的观察性队列研究来解释混杂的概念以及回归分析的用途。最后,将讨论在一致性研究中使用适当的一致性分析与相关性分析以避免牙科研究中常见的陷阱。

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