降钙素原在儿科重症监护病房的应用。
Procalcitonin use in a pediatric intensive care unit.
作者信息
Cies Jeffrey J, Chopra Arun
机构信息
From the *St. Christopher's Hospital for Children, Philadelphia, PA; †Drexel University College of Medicine, Philadelphia, PA; ‡Alfred I duPont Hospital for Children, Wilmington, DE; §NYU Langone Medical Center, New York, NY; and ¶NYU School of Medicine, New York, NY.
出版信息
Pediatr Infect Dis J. 2014 Sep;33(9):984-6. doi: 10.1097/INF.0000000000000370.
We evaluated whether procalcitonin (PCT) might aid diagnosing serious bacterial infections in a general pediatric intensive care unit population. Two-hundred and one patients accounted for 332 PCT samples. A PCT ≥1.45 ng/mL had a positive predictive value of 30%, a negative predictive value of 93% and a sensitivity of 72% and a specificity of 75%. These data suggest PCT can assist in identifying patients without serious bacterial infections and limit antimicrobial use.
我们评估了降钙素原（PCT）是否有助于诊断普通儿科重症监护病房人群中的严重细菌感染。201名患者提供了332份PCT样本。PCT≥1.45 ng/mL时，阳性预测值为30%，阴性预测值为93%，敏感性为72%，特异性为75%。这些数据表明，PCT有助于识别无严重细菌感染的患者并限制抗菌药物的使用。
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