Yoon K Lira, LeMoult Joelle, Joormann Jutta
Department of Psychology, University of Maine, Orono, ME 04469-5782, USA.
Department of Psychology, Stanford University, Stanford, CA 94305, USA.
J Behav Ther Exp Psychiatry. 2014 Sep;45(3):368-74. doi: 10.1016/j.jbtep.2014.03.004. Epub 2014 Apr 4.
Interference from irrelevant negative material might be a key mechanism underlying intrusive ruminative thoughts in depression. Considering commonalities between depression and social anxiety and the presence of similar intrusive thoughts in social anxiety, the current study was designed to assess whether interference from irrelevant material in working memory is specific to depression or is also present in social anxiety disorder.
To examine the effects of irrelevant emotional material on working memory performance, participants memorized two lists of words on each trial and were subsequently instructed to ignore one of the lists. Participants were then asked to indicate whether a probe word belonged to the relevant list or not.
Compared to control and social anxiety groups, the depression groups (both pure and comorbid with social anxiety disorder) exhibited greater difficulties removing irrelevant emotional material from working memory (i.e., greater intrusion effects). Greater intrusion effects were also associated with increased rumination.
Although we included three clinical groups (depression, social anxiety, and the comorbid groups), the results are based on a relatively small number of participants.
The results indicate that difficulties removing irrelevant material from working memory might be unique to depression, and the ability to inhibit irrelevant information is relatively preserved in social anxiety disorder.
来自无关负面材料的干扰可能是抑郁症中侵入性反刍思维背后的关键机制。考虑到抑郁症与社交焦虑症之间的共性以及社交焦虑症中存在类似的侵入性思维,本研究旨在评估工作记忆中无关材料的干扰是抑郁症所特有的,还是在社交焦虑障碍中也存在。
为了检验无关情绪材料对工作记忆表现的影响,参与者在每次试验中记忆两组单词列表,随后被指示忽略其中一组。然后要求参与者指出一个探测词是否属于相关列表。
与对照组和社交焦虑症组相比,抑郁症组(包括单纯抑郁症组和合并社交焦虑障碍的抑郁症组)在从工作记忆中去除无关情绪材料方面表现出更大的困难(即更大的侵入效应)。更大的侵入效应也与反刍思维增加有关。
尽管我们纳入了三个临床组(抑郁症组、社交焦虑症组和合并症组),但结果是基于相对较少的参与者得出的。
结果表明,从工作记忆中去除无关材料的困难可能是抑郁症所特有的,而在社交焦虑障碍中,抑制无关信息的能力相对保留。