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克罗默相关抗原——衰变加速因子上的血型决定簇。

Cromer-related antigens--blood group determinants on decay-accelerating factor.

作者信息

Daniels G

机构信息

Medical Research Council Blood Group Unit, London, UK.

出版信息

Vox Sang. 1989;56(4):205-11. doi: 10.1111/j.1423-0410.1989.tb02030.x.

DOI:10.1111/j.1423-0410.1989.tb02030.x
PMID:2474898
Abstract

Cromer-related antigens, a series of blood group antigens phenotypically related to each other through various serological characteristics, have recently been shown to be carried on the complement regulatory glycoprotein decay-accelerating factor (DAF). Cromer-related antigens, therefore, represent a number of inherited variants and polymorphisms of DAF. The Inab phenotype, a 'Cromer-null' phenotype in which the red cells lack all Cromer-related antigens, appears to be an inherited DAF deficiency.

摘要

克罗默相关抗原是一系列通过各种血清学特征在表型上相互关联的血型抗原,最近已被证明存在于补体调节糖蛋白衰变加速因子(DAF)上。因此,克罗默相关抗原代表了DAF的一些遗传变异和多态性。Inab表型是一种“无克罗默”表型,其中红细胞缺乏所有克罗默相关抗原,似乎是一种遗传性DAF缺乏症。

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