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[短潜伏期皮层体感诱发电位在评估后颅窝手术后早期吞咽障碍中的应用]

[Application of shot-latency cortical somato-sensory evoked potentials for evaluation of swallowing disorders in early period after posterior fossa surgery].

作者信息

Podlepich V V, Savin I A, Goriachev A S, Oshorov A V, Shimanskiĭ V N, Madorskiĭ S V, Sokolova E Iu, Matskovskiĭ I V, Anan'ev E P, Nichaeva A G

出版信息

Anesteziol Reanimatol. 2014 Jan-Feb(1):47-52.

PMID:24749310
Abstract

UNLABELLED

Main tasks of early postoperative period in patients after posterior fossa surgery are the timely and safe weaning from mechanical ventilation and extubation. For clinical assessment of the hypopharynx function we use an algorithm developed in the intensive care unit (ICU) of the Burdenko Scientific Research Institute of Neurosurgery. Disadvantages of the clinical test for assessment of patient's readiness for extubation are subjectivity and impossibility to use it in conditions of even superficial sedation. Shot-latency somato-sensory evoked potentials (SSEP) can be applied in conditions of sedation and objectify the brain stem deficit. The goal of the study was to define the changes of cortical SSEP in patients with disorders of swallowing after posterior fossa surgery. To assess the swallowing disorders we used a scale of swallowing disorders in intubated patients with brain stem damage. We compared results of cortical SSEP, test of swallowing disorders in intubated patients and clinical results of extubation. 17 patients with tumors of posterior fossa were included in the study. All patients were divided into two groups depending on duration of mechanical ventilation. Patients of the group-1 were successfully extubated in 4.5 hours. Patients of the group-2 were mechanically ventilated more than 15 hours because of impossibility to pass the test of readiness for extubation.

RESULTS

Central conduction time symmetry index after the surgery was lower in the group-1 than in group-2. There was inverse correlation between amplitude of cortical response N20 and time from the patient's admission to the ICU until the moment of extubation.

CONCLUSIONS

Asymmetry of central conduction time and decreasing of N20 amplitude can be used as additional predictor of swallowing disorder.

摘要

未标注

后颅窝手术后患者术后早期的主要任务是及时、安全地撤机和拔管。为了对下咽功能进行临床评估,我们使用了由布尔坚科神经外科科研所重症监护病房(ICU)开发的一种算法。用于评估患者拔管准备情况的临床测试的缺点是主观性强,且在患者即使处于浅镇静状态时也无法使用。短潜伏期体感诱发电位(SSEP)可在镇静状态下应用,并能客观反映脑干功能缺损情况。本研究的目的是确定后颅窝手术后吞咽功能障碍患者皮层SSEP的变化。为评估吞咽功能障碍,我们使用了脑干损伤插管患者吞咽功能障碍量表。我们比较了皮层SSEP结果、插管患者吞咽功能障碍测试结果和拔管的临床结果。17例后颅窝肿瘤患者纳入本研究。所有患者根据机械通气时间分为两组。第一组患者在4.5小时内成功拔管。第二组患者因无法通过拔管准备测试而机械通气超过15小时。

结果

术后第一组的中枢传导时间对称指数低于第二组。皮层反应N20的波幅与患者入住ICU至拔管时刻之间的时间呈负相关。

结论

中枢传导时间不对称和N20波幅降低可作为吞咽功能障碍的额外预测指标。

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