Ditchfield Jessica A, Granger Emily, Spratt Phillip, Jansz Paul, Dhital Kumud, Farnsworth Alan, Hayward Chris
Faculty of Medicine, University of New South Wales, Sydney NSW 2052, Australia.
Department of Cardiothoracic Surgery, St Vincent's Hospital, Darlinghurst, Sydney NSW 2010, Australia.
Heart Lung Circ. 2014 Sep;23(9):841-6. doi: 10.1016/j.hlc.2014.03.017. Epub 2014 Mar 26.
With improved life expectancy more octogenarians now present with aortic valve disease. Cardiac surgery in this group of patients has previously been considered high risk due to co-morbidities and challenges of rehabilitation. This study seeks to challenge the concept of octogenarian cardiac surgery "unsuitability" by analysing operative outcomes and long term survival following aortic valve replacement.
Eighty-seven consecutive patients undergoing aortic valve replacement between 2000 and 2009 at St Vincent's Hospital were retrospectively identified. Statistical analysis was performed using SPSS (version 15 and 19).
The average age was 82.7 ± 2.4 years. The mean logistic EuroSCORE was 18.86 ± 14.11. Post-operatively, four patients required insertion of a permanent pacemaker (4.6%) and five patients had a myocardial infarction (5.8%). In-hospital mortality was 3.4%. Follow-up was 93.1% complete. One-year survival was 92.9%, three-year survival was 86.7% and five-year survival was 75.0%. At follow-up 98.1% of patients were New York Heart Association (NYHA) Class I or II.
Results were excellent despite reasonable co-morbidities and Euroscore risk. Survival was impressive and the NYHA class reflected the success of the surgery in relieving the pathological aortic valve process. Patient age should not be the primary exclusion for cardiac surgery for aortic valve disease.
随着预期寿命的提高,现在有更多的八旬老人患有主动脉瓣疾病。由于并存疾病和康复挑战,此前这组患者的心脏手术被认为风险很高。本研究旨在通过分析主动脉瓣置换术后的手术结果和长期生存率,对八旬老人心脏手术“不适合”这一概念提出质疑。
回顾性确定了2000年至2009年在圣文森特医院连续接受主动脉瓣置换术的87例患者。使用SPSS(版本15和19)进行统计分析。
平均年龄为82.7±2.4岁。平均逻辑欧洲心脏手术风险评估系统(EuroSCORE)评分为18.86±14.11。术后,4例患者需要植入永久性起搏器(4.6%),5例患者发生心肌梗死(5.8%)。住院死亡率为3.4%。随访完成率为93.1%。1年生存率为92.9%,3年生存率为86.7%,5年生存率为75.0%。随访时,98.1%的患者为纽约心脏协会(NYHA)I级或II级。
尽管存在合理的并存疾病和EuroSCORE风险,但结果良好。生存率令人印象深刻,NYHA分级反映了手术在缓解病理性主动脉瓣病变方面的成功。患者年龄不应成为主动脉瓣疾病心脏手术的主要排除因素。