直径大于5厘米的胃胃肠道间质瘤（GISTs）的手术策略：腹腔镜手术是可行、安全且在肿瘤学上可接受的。
Surgical strategy for the gastric gastrointestinal stromal tumors (GISTs) larger than 5 cm: laparoscopic surgery is feasible, safe, and oncologically acceptable.
作者信息
Takahashi Tsuyoshi, Nakajima Kiyokazu, Miyazaki Yasuaki, Miyazaki Yasuhiro, Kurokawa Yukinori, Yamasaki Makoto, Miyata Hiroshi, Takiguchi Shuji, Nishida Toshirou, Mori Masaki, Doki Yuichiro
机构信息
*Department of Surgery, Osaka University Graduate School of Medicine, Suita †Department of Surgery, Osaka Police Hospital, Osaka, Japan.
出版信息
Surg Laparosc Endosc Percutan Tech. 2015 Apr;25(2):114-8. doi: 10.1097/SLE.0000000000000039.
BACKGROUND
The efficacy and feasibility of laparoscopic surgery (LAP) for gastric GISTs >5 cm has not been adequately assessed. Here we investigated the clinical outcomes of these patients.
PATIENTS AND METHODS
Twenty-seven consecutive patients who underwent resection for gastric GISTs >5 cm were enrolled in this retrospective study. We assessed the tumor characteristics, surgical outcomes, tumor recurrence, and patient survival in the open surgery (OPEN) group and in the LAP group.
RESULTS
The tumor size in the OPEN group was larger than that in the LAP group, but there were no differences in the mitotic count. There were no differences in operative complications. Finally, there were no differences in the disease-free and no patients in the LAP group died.
CONCLUSIONS
In patients with gastric GISTs >5 cm, LAP can be performed with outcomes equivalent to those of OPEN if patient selection and intraoperative judgment are appropriate.
背景
腹腔镜手术（LAP）治疗直径>5 cm的胃间质瘤的疗效和可行性尚未得到充分评估。在此，我们研究了这些患者的临床结局。
患者与方法
本回顾性研究纳入了27例连续接受直径>5 cm胃间质瘤切除术的患者。我们评估了开放手术（OPEN）组和LAP组的肿瘤特征、手术结局、肿瘤复发和患者生存情况。
结果
OPEN组的肿瘤大小大于LAP组，但有丝分裂计数无差异。手术并发症无差异。最后，无病生存率无差异，且LAP组无患者死亡。
结论
对于直径>5 cm的胃间质瘤患者，如果患者选择和术中判断合适，LAP手术的效果与OPEN手术相当。
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