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腔内治疗髂外动脉闭塞性疾病:中期结果。

Endovascular treatment of external iliac artery occlusive disease: midterm results.

机构信息

Servicio de Angiología y Cirugía Vascular, Hospital Clínico San Carlos, Universidad Complutense, Madrid, Spain.

出版信息

J Endovasc Ther. 2014 Apr;21(2):223-9. doi: 10.1583/13-4443MR.1.

DOI:10.1583/13-4443MR.1
PMID:24754281
Abstract

PURPOSE

To report midterm outcomes for endovascular treatment of external iliac artery (EIA) occlusive disease and assess possible factors affecting patency.

METHODS

A retrospective analysis was conducted of 99 consecutive patients (91 men; mean age 67.3 years) with claudication (n=70) or critical limb ischemia (n=29) owing to occlusive EIA disease treated at our center from January 2005 to June 2012. The majority of lesions (79/108) were TASC A/B. Lesions were a mean 42.2 mm long (range 10-125); 43/108 affected the distal third of the EIA. Balloon angioplasty alone was performed in 7 limbs, while the remaining 101 lesions were stented (65 self-expanding, 24 balloon-expandable, and 12 covered). Clinical and hemodynamic follow-up was performed at 1, 3, 6, and 12 months after therapy and yearly thereafter. The factors examined were procedure characteristics and patency rates.

RESULTS

Over a median follow-up of 27.5 months (range 1-89), there were 2 (1.9%) early occlusions followed by a successful reintervention, 4 late occlusions, and 5 hemodynamic failures followed by 7 reinterventions. These events led to primary and secondary patency rates at 30 months of 89.7% and 94.1%, respectively. No differences in patency rates were detected according to age, clinical state, or comorbidity. Use of covered stents (p=0.006) was the only variable associated with lower primary patency rates.

CONCLUSION

Endovascular therapy to treat TASC A/B lesions of the EIA yielded good short and midterm patency and low early morbidity and mortality. Lesions involving the distal third of the EIA treated by simple angioplasty ± stenting fared worse. No clinical factors could be correlated with patency.

摘要

目的

报告血管内治疗髂外动脉(EIA)闭塞性疾病的中期结果,并评估可能影响通畅率的因素。

方法

对 2005 年 1 月至 2012 年 6 月在我中心接受治疗的 99 例(91 例男性;平均年龄 67.3 岁)因 EIA 闭塞性疾病出现间歇性跛行(n=70)或临界肢体缺血(n=29)的连续患者进行回顾性分析。大多数病变(79/108)为 TASC A/B 型。病变长度平均为 42.2mm(范围 10-125mm);43/108 累及 EIA 远端三分之一。7 条肢体仅行单纯球囊血管成形术,101 条病变采用支架置入(65 条自膨式,24 条球囊扩张式,12 条覆膜式)。治疗后 1、3、6 和 12 个月以及此后每年进行临床和血液动力学随访。检查的因素包括手术特点和通畅率。

结果

中位随访 27.5 个月(范围 1-89 个月)后,2 例(1.9%)发生早期闭塞,经成功再次介入治疗后恢复通畅,4 例发生晚期闭塞,5 例发生血液动力学失败,随后进行 7 次再次介入治疗。这些事件导致 30 个月时的原发性和继发性通畅率分别为 89.7%和 94.1%。年龄、临床状态或合并症均未导致通畅率差异。覆膜支架的使用(p=0.006)是与原发性通畅率降低相关的唯一变量。

结论

血管内治疗 TASC A/B 型 EIA 病变可获得良好的短期和中期通畅率,且早期发病率和死亡率较低。单纯血管成形术±支架置入治疗 EIA 远端三分之一病变的效果较差。无临床因素与通畅率相关。

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