Amatori Stefano, Ambrosi Gianluca, Borgogelli Elisa, Fanelli Mirco, Formica Mauro, Fusi Vieri, Giorgi Luca, Macedi Eleonora, Micheloni Mauro, Paoli Paola, Rossi Patrizia, Tassoni Aurora
Department of Base Sciences and Fundamentals, Chemistry Section, University of Urbino "Carlo Bo" , P.zza Rinascimento 6, I-61029 Urbino, Italy.
Inorg Chem. 2014 May 5;53(9):4560-9. doi: 10.1021/ic5001649. Epub 2014 Apr 23.
Ligand L (2,6-bis{[7-(7-nitrobenzo[1,2,5]oxadiazole-4-yl)-3,10-dimethyl-1,4,7,10-tetraazacyclododeca-1-yl]methyl}phenol) is a fluorescent sensor that is useful for detecting Cu(II), Zn(II), and Cd(II). Some of the complexes formed are able to sense the presence of halides in solution. L passes through the cellular membrane, becoming fluorescent inside cells. The H(-1)L- species is able to form dinuclear complexes with [M(2)H(-1)L]3+ stoichiometry with Cu(II), Zn(II), and Cd(II) ions, experiencing a CHEF effect upon metal coordination in an acetonitrile/water 95:5 (v/v) solution. In all three of the complexes investigated, the metal cations are coordinatively unsaturated and can therefore bind secondary ligands as anionic species. The crystal structure of Cd(2)(H(-1)L)Cl(2)·4H(2)O is discussed. The Zn(II) complex behaves as an OFF-ON sensor for fluoride and chloride anions.
配体L（2,6 - 双{[7 - （7 - 硝基苯并[1,2,5]恶二唑 - 4 - 基） - 3,10 - 二甲基 - 1,4,7,10 - 四氮杂环十二烷 - 1 - 基]甲基}苯酚）是一种荧光传感器，可用于检测铜（II）、锌（II）和镉（II）。形成的一些配合物能够检测溶液中卤化物的存在。L可穿过细胞膜，在细胞内发出荧光。H(-1)L-物种能够与铜（II）、锌（II）和镉（II）离子以[M(2)H(-1)L]3+化学计量比形成双核配合物，在乙腈/水95:5（v/v）溶液中金属配位时会产生CHEF效应。在所研究的所有三种配合物中，金属阳离子配位不饱和，因此可以作为阴离子物种结合二级配体。讨论了Cd(2)(H(-1)L)Cl(2)·4H(2)O的晶体结构。锌（II）配合物对氟离子和氯离子表现为关闭 - 开启型传感器。
