Division of General Internal Medicine, Department of Medicine, University of Washington, 4245 Roosevelt Way Northeast, Box 354760, Seattle, WA 98105, USA.
Med Clin North Am. 2014 May;98(3):625-43. doi: 10.1016/j.mcna.2014.01.012. Epub 2014 Mar 21.
Involuntary weight loss remains an important and challenging clinical problem, with a high degree of morbidity and mortality. Because of the frequency of finding a serious underlying diagnosis, clinicians must be thorough in assessment, keeping in mind a broad range of possible causes. Although prediction scores exist, they have not been broadly validated; therefore, clinical judgment remains ever essential.
非自愿性体重减轻仍然是一个重要且具有挑战性的临床问题,具有很高的发病率和死亡率。由于经常发现严重的潜在诊断,临床医生必须在评估时彻底,牢记可能的广泛原因。尽管存在预测评分,但尚未广泛验证;因此,临床判断仍然至关重要。